The high-fat diet consisted of cholesterol, hydrogenated coconut oil, and cholic acid. In the blood serum and in liver homogenate lipid content, cholesterol, and triglycerides were assayed. Cytochrome P-450 concentration in liver microsomes was also estimated. In animals receiving selenium and vitamin E, the content of lipid fractions in the blood serum and liver homogenate fell, while the cytochrome P-450 content in the liver microsomes was markedly elevated. The intensified protective effect of vitamin E and selenium applied in combination against changes induced in the liver of animals receiving a HFD was confirmed by macroscopic and microscopic examination of the organ.
机构:
Mansoura Fac Med, Anat Dept, Mansoura, Egypt
Almaarefa Coll Med, Riyadh, Saudi ArabiaMansoura Fac Med, Anat Dept, Mansoura, Egypt
El-Sherbiny, Mohamed
Eldosoky, Mohamed
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Mansoura Fac Med, Med Physiol Dept, Mansoura, EgyptMansoura Fac Med, Anat Dept, Mansoura, Egypt
Eldosoky, Mohamed
El-Shafey, Mohamed
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机构:
Mansoura Fac Med, Anat Dept, Mansoura, Egypt
Fakeeh Coll Med Sci, Jeddah, Saudi ArabiaMansoura Fac Med, Anat Dept, Mansoura, Egypt
El-Shafey, Mohamed
Othman, Gamal
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机构:
Mansoura Fac Med, Med Biochem Dept, Mansoura, Egypt
Almaarefa Coll Med, Riyadh, Saudi ArabiaMansoura Fac Med, Anat Dept, Mansoura, Egypt
Othman, Gamal
Elkattawy, Hany A.
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机构:
Zagazig Fac Med, Zagazig Obes Management & Res Unit, Med Physiol Dept, Zagazig, Egypt
Almaarefa Coll Med, Riyadh, Saudi ArabiaMansoura Fac Med, Anat Dept, Mansoura, Egypt
Elkattawy, Hany A.
Bedir, Tamer
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机构:
Mansoura Fac Med, Med Microbiol & Immunol Dept, Mansoura, EgyptMansoura Fac Med, Anat Dept, Mansoura, Egypt
Bedir, Tamer
Elsherbiny, Nehal Mohsen
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机构:
Univ Tabuk, Fac Pharm, Dept Pharmaceut Sci, Tabuk, Saudi Arabia
Mansoura Univ, Fac Pharm, Dept Biochem, Mansoura, EgyptMansoura Fac Med, Anat Dept, Mansoura, Egypt