Making the Case for Molecular Staging of Malignant Pleural Mesothelioma

被引：10

作者：

Bueno, Raphael ^{[1
]}

机构：

[1] Harvard Med Sch, Brigham & Womens Hosp, Div Thorac Surg, Boston, MA USA

来源：

SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY | 2009年 / 21卷 / 02期

关键词：

mesothelioma; predictive test; gene ratio test; RNA expression; outcome in mesothelioma; staging of mesothelioma; surgery in mesothelioma;

D O I：

10.1053/j.semtcvs.2009.07.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Malignant pleural mesothelioma is an aggressive malignancy for which surgical treatment is an option for a subset of patients. A gene ratio test based on the relative expression levels of four genes has been validated in clinical trials to predict which patients will benefit from surgical therapy. A description of the test properties and the independent predictors for outcome are provided. © 2009 Elsevier Inc. All rights reserved.

引用

页码：188 / 193

页数：6

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