Making the Case for Molecular Staging of Malignant Pleural Mesothelioma

被引：10
|
作者：
Bueno, Raphael [1 ]
机构：
[1] Harvard Med Sch, Brigham & Womens Hosp, Div Thorac Surg, Boston, MA USA
来源：
SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY | 2009年 / 21卷 / 02期
关键词：
mesothelioma; predictive test; gene ratio test; RNA expression; outcome in mesothelioma; staging of mesothelioma; surgery in mesothelioma;
D O I：
10.1053/j.semtcvs.2009.07.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Malignant pleural mesothelioma is an aggressive malignancy for which surgical treatment is an option for a subset of patients. A gene ratio test based on the relative expression levels of four genes has been validated in clinical trials to predict which patients will benefit from surgical therapy. A description of the test properties and the independent predictors for outcome are provided. © 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码：188 / 193
页数：6
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