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Making the Case for Molecular Staging of Malignant Pleural Mesothelioma
被引:10
|作者:
Bueno, Raphael
[1
]
机构:
[1] Harvard Med Sch, Brigham & Womens Hosp, Div Thorac Surg, Boston, MA USA
关键词:
mesothelioma;
predictive test;
gene ratio test;
RNA expression;
outcome in mesothelioma;
staging of mesothelioma;
surgery in mesothelioma;
D O I:
10.1053/j.semtcvs.2009.07.003
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Malignant pleural mesothelioma is an aggressive malignancy for which surgical treatment is an option for a subset of patients. A gene ratio test based on the relative expression levels of four genes has been validated in clinical trials to predict which patients will benefit from surgical therapy. A description of the test properties and the independent predictors for outcome are provided. © 2009 Elsevier Inc. All rights reserved.
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页码:188 / 193
页数:6
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