Making the Case for Molecular Staging of Malignant Pleural Mesothelioma

被引:10
|
作者
Bueno, Raphael [1 ]
机构
[1] Harvard Med Sch, Brigham & Womens Hosp, Div Thorac Surg, Boston, MA USA
关键词
mesothelioma; predictive test; gene ratio test; RNA expression; outcome in mesothelioma; staging of mesothelioma; surgery in mesothelioma;
D O I
10.1053/j.semtcvs.2009.07.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Malignant pleural mesothelioma is an aggressive malignancy for which surgical treatment is an option for a subset of patients. A gene ratio test based on the relative expression levels of four genes has been validated in clinical trials to predict which patients will benefit from surgical therapy. A description of the test properties and the independent predictors for outcome are provided. © 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:188 / 193
页数:6
相关论文
共 50 条
  • [1] The Staging of Malignant Pleural Mesothelioma
    Euhus, Caleb J.
    Ripley, R. Taylor
    THORACIC SURGERY CLINICS, 2020, 30 (04) : 425 - +
  • [2] Malignant pleural mesothelioma: predictors and staging
    Richards, William G.
    ANNALS OF TRANSLATIONAL MEDICINE, 2017, 5 (11)
  • [3] Malignant pleural mesothelioma: Staging systems
    Van Schil, P
    LUNG CANCER, 2005, 49 : S45 - S48
  • [4] Review of staging and diagnosis of malignant pleural mesothelioma
    Jordan, Sean
    Nitsche, Lindsay
    Yendamuri, Sai
    AME SURGICAL JOURNAL, 2022, 2
  • [5] Diagnostic tools and staging of malignant pleural mesothelioma
    Powers, Amy
    Carbone, Michele
    LUNG CANCER MANAGEMENT, 2015, 4 (05) : 211 - 218
  • [6] Staging and response to therapy of malignant pleural mesothelioma
    Heelan, R
    LUNG CANCER, 2004, 45 : S59 - S61
  • [7] Surgical staging and resection of malignant pleural mesothelioma
    Brown, Lawrence B.
    Corl, Frank
    Blackmon, Shanda H.
    JOURNAL OF THORACIC DISEASE, 2020, 12 (12) : 7467 - 7480
  • [8] Staging algorithm for diffuse malignant pleural mesothelioma
    Zielinski, Marcin
    Hauer, Jolanta
    Hauer, Lukasz
    Pankowski, Juliusz
    Nabialek, Tomasz
    Szlubowski, Artur
    INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, 2010, 10 (02) : 185 - 189
  • [9] Staging and evaluating responses in malignant pleural mesothelioma
    Hillerdal, G
    LUNG CANCER, 2004, 43 (01) : 75 - 76
  • [10] Updates in Staging and Management of Malignant Pleural Mesothelioma
    Wolf, Andrea S.
    Flores, Raja M.
    SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, 2020, 29 (04) : 603 - 612