THE PROTECTIVE ROLE OF HUMORAL NEUTRALIZING ANTIBODY IN THE NIH POTENCY TEST FOR RABIES VACCINES

被引：36
|
作者：
WUNDERLI, PS [1 ]
SHADDOCK, JH [1 ]
SCHMID, DS [1 ]
MILLER, TJ [1 ]
BAER, GM [1 ]
机构：
[1] SMITHKLINE BEECHAM ANIM HLTH,KING OF PRUSSIA,PA 19406
来源：
VACCINE | 1991年 / 9卷 / 09期
关键词：
RABIES; HUMORAL NEUTRALIZING ANTIBODY; NIH POTENCY TEST; MICE;
D O I：
10.1016/0264-410X(91)90188-C
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Intraperitoneal vaccination of mice with rabies vaccine results in both dosage-dependent rabies virus neutralizing antibody titres and protection from lethal intracerebral (i.c.) challenge with fixed strain CVS rabies virus. Pre-exposure adoptive intravenous transfer of naive or immune cells did not significantly protect naive Balb/c mice from lethal i.c. CVS challenge, but immune serum and anti-rabies glycoprotein monoclonal antibodies (individually and in combination) did confer significant protection when administered before or up to 24 h after lethal i.c. rabies virus challenge.
引用
收藏
页码：638 / 642
页数：5
相关论文
共 50 条
  • [21] Evaluation of an improved rapid neutralizing antibody detection test (RAPINA) for qualitative and semiquantitative detection of rabies neutralizing antibody in humans and dogs
    Nishizono, Akira
    Yamada, Kentaro
    Khawplod, Pakamatz
    Shiota, Seiji
    Perera, Devika
    Matsumoto, Takashi
    Wimalaratne, Omala
    Mitui, Marcelo Takahiro
    Ahmed, Kamruddin
    VACCINE, 2012, 30 (26) : 3891 - 3896
  • [22] RABIES NEUTRALIZING ANTIBODY DETERMINATION BY THE INTERFERENCE INHIBITION TEST (IIT) AND THE MOUSE NEUTRALIZATION TEST (MNT)
    NICHOLSON, KG
    HARRISON, P
    TURNER, GS
    JOURNAL OF BIOLOGICAL STANDARDIZATION, 1979, 7 (03): : 253 - 261
  • [23] POTENCY OF 2 RABIES VACCINES IN CATS AS DETERMINED BY ANTIBODY-ASSAY AND VIRULENT VIRUS CHALLENGE
    KIHM, U
    LAZAROWICZ, M
    BOMMELI, W
    ZUTTER, R
    COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 1982, 5 (1-3) : 227 - 232
  • [24] APPROACHES TO VALIDATION OF ANIMAL TEST SYSTEMS FOR ASSAY FOR PROTECTIVE POTENCY OF BCG VACCINES
    SMITH, DW
    HARDING, GE
    JOURNAL OF BIOLOGICAL STANDARDIZATION, 1977, 5 (02): : 131 - 138
  • [25] THE MOUSE VIBRIOCIDAL ANTIBODY-TEST - A METHOD FOR MONITORING THE POTENCY OF CHOLERA VACCINES
    FORD, AW
    SEAGROATT, V
    ALTERMAN, L
    HAYHOE, J
    JOURNAL OF BIOLOGICAL STANDARDIZATION, 1982, 10 (01): : 47 - 57
  • [26] CONTROL OF ACTIVITY OF INACTIVE RABIES VACCINES - CRITICAL-STUDY OF NIH TEST BY EXPERIMENTAL-MODEL, THE PERIPHERIC TEST
    AUBERT, MFA
    ANDRAL, L
    BLANCOU, J
    JOURNAL OF BIOLOGICAL STANDARDIZATION, 1981, 9 (01): : 35 - 43
  • [27] Development of competitive inhibition ELISA as an effective potency test to analyze human rabies vaccines and assessment of the antigenic epitope of rabies glycoprotein
    Soni, Dipen
    Sahoo, Itishree
    Mallya, Asha D.
    Kamthe, Praveen
    Sahai, Ashish
    Goel, Sunil Kumar
    Kulkarni, Prasad S.
    Dhere, Rajeev M.
    JOURNAL OF IMMUNOLOGICAL METHODS, 2021, 492
  • [28] Potency test of inactivated Newcastle disease vaccines by monoclonal antibody blocking ELISA
    Horváth, E
    Czifra, G
    Nagy, E
    Engström, B
    Mérza, M
    VACCINE, 1999, 17 (23-24) : 2969 - 2973
  • [29] The rapid fluorescent focus inhibition test is a suitable method for batch potency testing of inactivated rabies vaccines
    Kraemer, B.
    Schildger, H.
    Behrensdorf-Nicol, H. A.
    Hanschmann, K. M.
    Duchow, K.
    BIOLOGICALS, 2009, 37 (02) : 119 - 126
  • [30] POTENCY TEST OF FOOT-AND-MOUTH-DISEASE (FMD) VACCINES - CORRELATION BETWEEN RESPONSE TO CHALLENGE AND CORRESPONDING NEUTRALIZING ANTIBODY-TITERS OF VACCINATED CATTLE
    BENGELSDORFF, HJ
    BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT, 1989, 102 (06): : 193 - 198
12345