N-(3-Chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine

被引：2

作者：

Uwabagira, Nadine ^{[1
]}

Sarojini, Balladka Kunhana ^{[2
]}

Poojary, Boja ^{[3
]}

机构：

[1] Mangalore Univ, Div Biochem, Dept Studies Chem, Mangalore 574199, Karnataka, India

[2] Mangalore Univ, Dept Studies Ind Chem, Mangalore 574199, Karnataka, India

[3] Mangalore Univ, Dept Studies Chem, Mangalore 574199, Karnataka, India

来源：

MOLBANK | 2018年 / 01期

关键词：

3-chloro-2-methylphenylthiourea; thiazole amine; antibacterial activity;

D O I：

10.3390/M975

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The two precursors 3-chloro-2-methylphenylthiourea 2 and 4-fluorophenacyl bromide 4 are reacted under Hantzsch thiazole synthesis condition to yield the new compound N-(3-chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine 5. The IR, H-1-NMR, C-13-NMR and mass spectral data are presented, along with its in vitro antibacterial activity against Staphylococcus aureus and Chromobacterium violaceum.

引用

页数：5

共 50 条

[41] N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine
Jasinski, Jerry P.
Butcher, Ray J.
Al-Arique, Q. N. M. Hakim
Yathirajan, H. S.
Narayana, B.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O349 - U2369
[42] 3-Benzyl-2-(4-fluorophenyl)-1,3-thiazolidin-4-one
Gutierrez, Alexander
Insuasty, Braulio
Cobo, Justo
Glidewell, Christopher
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2011, 67 : O10 - O12
[43] 5-(4-Fluorophenyl)-2-(4-methylphenyl)-3-methylsulfanyl-1-benzofuran
Choi, Hong Dae
Seo, Pil Ja
Lee, Uk
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : O258 - +
[44] 5-(4-Fluorophenyl)-3-(4-methylphenyl)-1-phenyl-2-pyrazoline
Guo, Huan-Mei
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O3223 - U3624
[45] 5-Chloro-2-(4-fluorophenyl)-3-methylsulfinyl-1-benzofuran
Choi, Hong Dae
Seo, Pil Ja
Son, Byeng Wha
Lee, Uk
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O2649 - U2750
[46] 1-acetyl-5-(4-fluorophenyl)-3-(4-methylphenyl)2-pyrazoline
Guo, Huan-Mei
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O3779 - U2772
[47] 5-Chloro-3-ethylsulfinyl-2-(4-fluorophenyl)-1-benzofuran
Choi, Hong Dae
Seo, Pil Ja
Son, Byeng Wha
Lee, Uk
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O402 - U2849
[48] 5-Chloro-2-(4-fluorophenyl)-3-phenylsulfinyl-1-benzofuran
Choi, Hong Dae
Seo, Pil Ja
Son, Byeng Wha
Lee, Uk
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O498 - U1798
[49] N-(3-Chloro-4-fluorophenyl)-2,2-diphenylacetamide
Praveen, A. S.
Jasinski, Jerry P.
Golen, James A.
Narayana, B.
Yathirajan, H. S.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2604 - U2121
[50] Crystal structures of 4-methoxy-N-(4-methylphenyl)benzenesulfonamide and N-(4-fluorophenyl)-4-methoxybenzenesulfonamide
Rodrigues, Vinola Z.
Preema, C. P.
Naveen, S.
Lokanath, N. K.
Suchetan, P. A.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : 1388 - +

← 1 2 3 4 5 →