N-(3-Chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine

被引：2
|
作者：
Uwabagira, Nadine [1 ]
Sarojini, Balladka Kunhana [2 ]
Poojary, Boja [3 ]
机构：
[1] Mangalore Univ, Div Biochem, Dept Studies Chem, Mangalore 574199, Karnataka, India
[2] Mangalore Univ, Dept Studies Ind Chem, Mangalore 574199, Karnataka, India
[3] Mangalore Univ, Dept Studies Chem, Mangalore 574199, Karnataka, India
来源：
MOLBANK | 2018年 / 01期
关键词：
3-chloro-2-methylphenylthiourea; thiazole amine; antibacterial activity;
D O I：
10.3390/M975
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The two precursors 3-chloro-2-methylphenylthiourea 2 and 4-fluorophenacyl bromide 4 are reacted under Hantzsch thiazole synthesis condition to yield the new compound N-(3-chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine 5. The IR, H-1-NMR, C-13-NMR and mass spectral data are presented, along with its in vitro antibacterial activity against Staphylococcus aureus and Chromobacterium violaceum.
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页数：5
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