The subcellular localization of 17 beta-hydroxysteroid dehydrogenase type 4 and its interaction with actin

被引:16
|
作者
Markus, M [1 ]
Husen, B [1 ]
Adamski, J [1 ]
机构
[1] MAX PLANCK INST EXPTL ENDOCRINOL,D-30625 HANNOVER,GERMANY
来源
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1995年 / 55卷 / 5-6期
关键词
D O I
10.1016/0960-0760(95)00213-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The porcine 17 beta-hydroxysteroid dehydrogenase type 4 is the key enzyme for the inactivation of estradiol. Its localization in peroxisomes was proven by immunogold electron microscopy. Interactions of the 17 beta-hydroxysteroid dehydrogenase with cytoskeletal proteins might be mandatory for a topical assignment of enzymatic activity to defined subcellular compartments.
引用
收藏
页码:617 / 621
页数:5
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