ASYMMETRIC-SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERIDINES BY NUCLEOPHILIC-ADDITION TO N-ACYLIMINIUM IONS BEARING PYRROLIDINE CHIRAL AUXILIARIES

被引：68

作者：

SUZUKI, H ^{[1
]}

AOYAGI, S ^{[1
]}

KIBAYASHI, C ^{[1
]}

机构：

[1] TOKYO COLL PHARM,HACHIOJI,TOKYO 19203,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期

关键词：

D O I：

10.1016/0040-4039(94)88092-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of carbon nucleophiles to cyclic N-acyliminium salts chirally modified by various optically active pyrrolidines leads to highly enantioselective synthesis of 2-substituted pyrrolidines and piperidines.

引用

页码：6119 / 6122

页数：4

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