ASYMMETRIC-SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERIDINES BY NUCLEOPHILIC-ADDITION TO N-ACYLIMINIUM IONS BEARING PYRROLIDINE CHIRAL AUXILIARIES

被引：68
|
作者：
SUZUKI, H [1 ]
AOYAGI, S [1 ]
KIBAYASHI, C [1 ]
机构：
[1] TOKYO COLL PHARM,HACHIOJI,TOKYO 19203,JAPAN
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期
关键词：
D O I：
10.1016/0040-4039(94)88092-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Addition of carbon nucleophiles to cyclic N-acyliminium salts chirally modified by various optically active pyrrolidines leads to highly enantioselective synthesis of 2-substituted pyrrolidines and piperidines.
引用
收藏
页码：6119 / 6122
页数：4
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