A molecular dynamics investigation on the inhibition mechanism of cholesteryl ester transfer protein by Anacetrapib

被引:0
|
作者
Mostafa Jamalan
Majid Zeinali
Mohammad Ali Ghaffari
机构
[1] Ahvaz Jundishapur University of Medical Sciences,Department of Biochemistry
[2] Research Institute of Petroleum Industry,Biotechnology Research Center
来源
关键词
Root-mean-square deviation; Inhibitory mechanism; Radius of gyration; Lipoprotein;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:62 / 69
页数:7
相关论文
共 50 条
  • [41] Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients
    Bloomfield, Daniel
    Carlson, Gary L.
    Sapre, Aditi
    Tribble, Diane
    McKenney, James M.
    Littlejohn, Thomas W., III
    Sisk, Christine McCrary
    Mitchel, Yale
    Pasternak, Richard C.
    AMERICAN HEART JOURNAL, 2009, 157 (02) : 352 - U20
  • [42] Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
    Tan, Eugene Y.
    Hartmann, Georgy
    Chen, Qing
    Pereira, Antonio
    Bradley, Scott
    Doss, George
    Zhang, Andy Shiqiang
    Ho, Jonathan Z.
    Braun, Matthew P.
    Dean, Dennis C.
    Tang, Wei
    Kumar, Sanjeev
    DRUG METABOLISM AND DISPOSITION, 2010, 38 (03) : 459 - 473
  • [43] Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib
    Miyares, Marta A.
    Davis, Kyle
    VASCULAR HEALTH AND RISK MANAGEMENT, 2012, 8 : 483 - 493
  • [44] Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib in Japanese patients with heterozygous familial hypercholesterolemia
    Arai, Hidenori
    Teramoto, Tamio
    Daida, Hiroyuki
    Ikewaki, Katsunori
    Maeda, Yuko
    Nakagomi, Mariko
    Shirakawa, Masayoshi
    Kakikawa, Taro
    Numaguchi, Hirotaka
    Johnson-Levonas, Amy O.
    Vaidya, Sanskruti
    Blaustein, Robert O.
    ATHEROSCLEROSIS, 2016, 249 : 215 - 223
  • [45] The cholesterol ester transfer protein inhibitor, anacetrapib
    Jialal, Ishwarlal
    Kaur, Jaspreet
    CURRENT OPINION IN LIPIDOLOGY, 2011, 22 (03) : 245 - 246
  • [46] CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITION AND REVERSE CHOLESTEROL TRANSPORT
    Sviridov, D.
    Tchoua, U.
    Mukhamedova, N.
    Niesor, E.
    Mizrahi, J.
    Maugeais, C.
    ATHEROSCLEROSIS SUPPLEMENTS, 2009, 10 (02)
  • [47] The inhibition of cholesteryl ester transfer protein: a long and winding road
    Rye, Kerry-Anne
    Barter, Philip J.
    JOURNAL OF LIPID RESEARCH, 2012, 53 (06) : 1039 - 1041
  • [48] MECHANISM OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITION BY NEUTRALIZING MONOCLONAL-ANTIBODIES (MABS)
    SWENSON, T
    TALL, A
    HESLER, C
    BROWN, M
    QUINET, E
    TROTTA, P
    HASLANGER, M
    GAETA, F
    MARCEL, Y
    MILNE, R
    ARTERIOSCLEROSIS, 1988, 8 (05): : A593 - A593
  • [49] Bound Phospholipids Assist Cholesteryl Ester Transfer in the Cholesteryl Ester Transfer Protein
    Keshavamurthy, Amrutha
    Revanasiddappa, Prasanna D.
    Dixit, Sneha M.
    Priyanka, Gandasi R.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 63 (10) : 3054 - 3067
  • [50] CHOLESTERYL ESTER TRANSFER PROTEIN
    不详
    LANCET, 1991, 338 (8768): : 666 - 667