A molecular dynamics investigation on the inhibition mechanism of cholesteryl ester transfer protein by Anacetrapib

被引：0
|
作者：
Mostafa Jamalan
Majid Zeinali
Mohammad Ali Ghaffari
机构：
[1] Ahvaz Jundishapur University of Medical Sciences,Department of Biochemistry
[2] Research Institute of Petroleum Industry,Biotechnology Research Center
来源：
Medicinal Chemistry Research | 2016年 / 25卷
关键词：
Root-mean-square deviation; Inhibitory mechanism; Radius of gyration; Lipoprotein;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：62 / 69
页数：7
相关论文
共 50 条
  • [31] Inhibition of cholesteryl ester transfer protein by rosenonolactone derivatives
    Kim, YK
    Son, KH
    Nam, JY
    Kim, SU
    Jeong, TS
    Lee, WS
    Bok, SH
    Kwon, BM
    Park, YJ
    Shin, JM
    JOURNAL OF ANTIBIOTICS, 1996, 49 (08): : 815 - 816
  • [32] Structural features of cholesteryl ester transfer protein: A molecular dynamics simulation study
    Lei, Dongsheng
    Zhang, Xing
    Jiang, Shengbo
    Cai, Zhaodi
    Rames, Matthew J.
    Zhang, Lei
    Ren, Gang
    Zhang, Shengli
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2013, 81 (03) : 415 - 425
  • [33] Inhibition of cholesteryl ester transfer protein increases cholesteryl ester content of large HDL independently of HDL-to-HDL homotypic transfer: In vitro vs in vivo comparison using anacetrapib and dalcetrapib
    Johns, Douglas G.
    Chen, Ying
    Wang, Sheng-Ping
    Castro-Perez, Jose
    Preyis, Stephen F.
    Roddy, Thomas P.
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 762 : 256 - 262
  • [34] Role of glycans in cholesteryl ester transfer protein revealed by molecular dynamics simulation
    Hao, Dongxiao
    Yang, Zhiwei
    Gao, Teng
    Tian, Zhiqi
    Zhang, Lei
    Zhang, Shengli
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 86 (08) : 882 - 891
  • [35] Cholesteryl Ester Transfer Protein Inhibition: A Dysfunctional Endothelium
    Westerterp, Marit
    Koetsveld, Joris
    Tall, Alan R.
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2010, 55 (05) : 456 - 458
  • [36] Insights into the Tunnel Mechanism of Cholesteryl Ester Transfer Protein through All-atom Molecular Dynamics Simulations
    Lei, Dongsheng
    Rames, Matthew
    Zhang, Xing
    Zhang, Lei
    Zhang, Shengli
    Ren, Gang
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (27) : 14034 - 14044
  • [37] Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein (vol 36, pg 994, 2016)
    Reyes-Soffer
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2016, 36 (05) : e51 - e51
  • [38] EFFECT OF HDL CORE FLUIDITY ON THE MECHANISM OF CHOLESTERYL ESTER TRANSFER BY THE HUMAN CHOLESTERYL ESTER TRANSFER PROTEIN (CETP)
    SWENSON, TL
    BROCIA, RW
    CIRCULATION, 1993, 88 (04) : 520 - 520
  • [39] Molecular genetics of plasma cholesteryl ester transfer protein
    Yamashita, S
    Sakai, N
    Hirano, K
    Arai, T
    Ishigami, M
    Maruyama, T
    Matsuzawa, Y
    CURRENT OPINION IN LIPIDOLOGY, 1997, 8 (02) : 101 - 110
  • [40] Cholesteryl Ester Transfer Protein Penetrates Lipoproteins For Cholesteryl Ester Transfer
    Ren, Gang
    Zhang, Shengli
    Cavigiolio, Giorgio
    Lei, Dongsheng
    Oda, Michael
    Weisgraber, Karl H.
    Rye, Kerry-Anne
    Pownall, Henry J.
    Qiu, Xiayang
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 36A - 36A
12345