Salicylaldehyde derivatives from a marine-derived fungus Eurotium sp. SCSIO F452

被引：0
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作者：
Weimao Zhong
Yuchan Chen
Xiaoyi Wei
Junfeng Wang
Weimin Zhang
Fazuo Wang
Si Zhang
机构：
[1] South China Sea Institute of Oceanology,CAS Key Laboratory of Tropical Marine Bio
[2] Chinese Academy of Sciences,resources and Ecology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology
[3] University of Chinese Academy of Sciences,State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology
[4] Guangdong Institute of Microbiology,Key Laboratory of Plant Resources Conservation and Sustainable Utilization
[5] South China Botanical Garden,undefined
[6] Chinese Academy of Sciences,undefined
来源：
The Journal of Antibiotics | 2021年 / 74卷
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摘要：
Two pairs of new salicylaldehyde derivative enantiomers, salicylaldehydiums A and B (1 and 2), along with five known analogues were isolated and identified from a marine-derived fungus Eurotium sp. SCSIO F452. Their structures and absolute configuration were determined by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculations. All the new optical pure enantiomers [(+)-1, (-)-1, (+)-2, (-)-2] were evaluated for their cytotoxic and antioxidative activities. Compound (-)-1 exhibited weak cytotoxic activity.
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页码：273 / 279
页数：6
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