Salicylaldehyde derivatives from a marine-derived fungus Eurotium sp. SCSIO F452

被引：0

作者：

Weimao Zhong

Yuchan Chen

Xiaoyi Wei

Junfeng Wang

Weimin Zhang

Fazuo Wang

Si Zhang

机构：

[1] South China Sea Institute of Oceanology,CAS Key Laboratory of Tropical Marine Bio

[2] Chinese Academy of Sciences,resources and Ecology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology

[3] University of Chinese Academy of Sciences,State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology

[4] Guangdong Institute of Microbiology,Key Laboratory of Plant Resources Conservation and Sustainable Utilization

[5] South China Botanical Garden,undefined

[6] Chinese Academy of Sciences,undefined

来源：

The Journal of Antibiotics | 2021年 / 74卷

关键词：

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学科分类号：

摘要：

Two pairs of new salicylaldehyde derivative enantiomers, salicylaldehydiums A and B (1 and 2), along with five known analogues were isolated and identified from a marine-derived fungus Eurotium sp. SCSIO F452. Their structures and absolute configuration were determined by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculations. All the new optical pure enantiomers [(+)-1, (-)-1, (+)-2, (-)-2] were evaluated for their cytotoxic and antioxidative activities. Compound (-)-1 exhibited weak cytotoxic activity.

引用

页码：273 / 279

页数：6

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