Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction

被引：0

作者：

Insun Park

Ashwini M. Londhe

Ji Woong Lim

Beoung-Geon Park

Seo Yun Jung

Jae Yeol Lee

Sang Min Lim

Kyoung Tai No

Jiyoun Lee

Ae Nim Pae

机构：

[1] Korea Institute of Science and Technology (KIST),Convergence Research Center for Diagnosis, Treatment and Care System of Dementia

[2] Yonsei University,Department of Biotechnology

[3] KyungHee University,Department of Converging Science and Technology

[4] Korea Institute of Science and Technology (KIST),Center for Neuro

[5] Korea University,Medicine

[6] Korea University of Science and Technology,School of Life Sciences and Biotechnology

[7] Sungshin University,Division of Bio

来源：

Journal of Computer-Aided Molecular Design | 2017年 / 31卷

关键词：

Cyclophilin D (CypD); Small molecule inhibitors; Mitochondrial permeability transition pore (mPTP); Alzheimer’s disease (AD); Energy-based pharmacophore; Molecular docking; Virtual screening;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：929 / 941

页数：12

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