Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin

被引:0
|
作者
Celme Vieira
Steffen Fetzer
Susanne K. Sauer
Stefano Evangelista
Beate Averbeck
Michaela Kress
Peter W. Reeh
Rocco Cirillo
Annalisa Lippi
Carlo A. Maggi
Stefano Manzini
机构
[1] Faculdade de Medicine de Riberào Preto,
[2] U.S.P.,undefined
[3] Brazil,undefined
[4] Department of Pharmacology,undefined
[5] Menarini Ricerche spa,undefined
[6] Pomezia (Rome),undefined
[7] Italy,undefined
[8] Preclinical Development,undefined
[9] Menarini Ricerche spa,undefined
[10] Via Sette Santi 1,undefined
[11] 50131 Firenze,undefined
[12] Italy,undefined
[13] Institute of Physiology and Experimental Pathophysiology,undefined
[14] University of Erlangen/Nürnberg,undefined
[15] Germany,undefined
关键词
Calcitonin gene-related peptide Capsaicin Carrageenan Castor oil Inflammation Ricinoleic acid Substance P;
D O I
暂无
中图分类号
学科分类号
摘要
We have investigated the pro- and anti-inflammatory effects of ricinoleic acid (RA), the main active principle of castor oil, in an experimental model of blepharitis induced by intradermal injection of carrageenan in the guinea-pig eyelid and its possible capsaicin-like mode of action on acutely dissociated rat dorsal root ganglia (DRG) neurons in vitro.
引用
收藏
页码:87 / 95
页数:8
相关论文
共 50 条
  • [31] Pro- and anti-inflammatory cytokines in children with febrile convulsions
    Straussberg, R
    Amir, J
    Harel, L
    Punsky, I
    Bessler, H
    PEDIATRIC NEUROLOGY, 2001, 24 (01) : 49 - 53
  • [32] Aptamers Against Pro- and Anti-Inflammatory Cytokines: A Review
    Maryam Boshtam
    Seddigheh Asgary
    Shirin Kouhpayeh
    Laleh Shariati
    Hossein Khanahmad
    Inflammation, 2017, 40 : 340 - 349
  • [33] Uncoupling of Pro- and Anti-Inflammatory Properties of Staphylococcus aureus
    Peres, Adam G.
    Stegen, Camille
    Li, Junbin
    Xu, An Qi
    Levast, Benoit
    Surette, Michael G.
    Cousineau, Benoit
    Desrosiers, Martin
    Madrenas, Joaquin
    INFECTION AND IMMUNITY, 2015, 83 (04) : 1587 - 1597
  • [34] Pro- versus anti-inflammatory cytokines:: Myth or reality
    Cavaillon, JM
    CELLULAR AND MOLECULAR BIOLOGY, 2001, 47 (04) : 695 - 702
  • [35] Regulation of inflammatory cytokine receptor expression by pro- and anti-inflammatory molecules
    Mantovani, A
    Sica, A
    Saccani, S
    Orlando, S
    Polentarutti, N
    Allavena, P
    Sozzani, S
    ASTHMA AND ALLERGIC DISEASES: PHYSIOLOGY, IMMUNOPHARMACOLOGY, AND TREATMENT, 1998, : 87 - 96
  • [36] Role of leukaemia inhibitory factor in inflammatory arthritis - Pro- or anti-inflammatory?
    Upadhyay, Aradhana
    Jazayeri, Jalal A.
    CYTOKINE, 2009, 48 (1-2) : 120 - 120
  • [37] Ellagic acid alleviates adjuvant induced arthritis by modulation of pro- and anti-inflammatory cytokines
    Allam, Gamal
    Mahdi, Emad A.
    Alzahrani, Abdullah M.
    Abuelsaad, Abdelaziz S.
    CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 41 (04) : 339 - 349
  • [38] Biphasic regulation of NF-κB activity underlies the pro- and anti-inflammatory actions of nitric oxide
    Connelly, L
    Palacios-Callender, M
    Ameixa, C
    Moncada, S
    Hobbs, AJ
    JOURNAL OF IMMUNOLOGY, 2001, 166 (06): : 3873 - 3881
  • [39] Serum cytokine levels in children with spectrum autism disorder: Differences in pro- and anti-inflammatory balance
    Kordulewska, Natalia Karolina
    Kostyra, Elzbieta
    Piskorz-Ogorek, Krystyna
    Moszynska, Malgorzata
    Cieslinska, Anna
    Fiedorowicz, Ewa
    Jarmolowska, Beata
    JOURNAL OF NEUROIMMUNOLOGY, 2019, 337
  • [40] Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages
    Gao, Yuan
    Chen, Xi
    Fang, Lei
    Liu, Fen
    Cai, Runlan
    Peng, Cheng
    Qi, Yun
    FREE RADICAL BIOLOGY AND MEDICINE, 2014, 72 : 104 - 112