Epigenetics and diabetes mellitus

被引:0
|
作者
Mohammed K. Rehan
机构
[1] Faculty of Medicine,Internal Medicine Department
[2] Beni Suef University,undefined
关键词
diabetes; epigenetic; gene expression;
D O I
10.4103/1110-7782.193890
中图分类号
学科分类号
摘要
Epigenetic mechanisms were shown to be involved in the control of endocrine cell fate decision, islet differentiation, β-cell identity, proliferation, and mature function. The pathologic mechanisms involved in the development of type 1 diabetes may include DNA methylation, histone modification, microRNA, and molecular mimicry. These mechanisms may act through the regulation of gene expression.
引用
收藏
页码:39 / 51
页数:12
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