Epigenetics and diabetes mellitus

被引：0
|
作者：
Mohammed K. Rehan
机构：
[1] Faculty of Medicine,Internal Medicine Department
[2] Beni Suef University,undefined
来源：
The Egyptian Journal of Internal Medicine | 2016年 / 28卷 / 2期
关键词：
diabetes; epigenetic; gene expression;
D O I：
10.4103/1110-7782.193890
中图分类号：
学科分类号：
摘要：
Epigenetic mechanisms were shown to be involved in the control of endocrine cell fate decision, islet differentiation, β-cell identity, proliferation, and mature function. The pathologic mechanisms involved in the development of type 1 diabetes may include DNA methylation, histone modification, microRNA, and molecular mimicry. These mechanisms may act through the regulation of gene expression.
引用
收藏
页码：39 / 51
页数：12
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