Impact of amyloid β aggregate maturation on antibody treatment in APP23 mice

被引：0
|
作者：
Karthikeyan Balakrishnan
Ajeet Rijal Upadhaya
Julia Steinmetz
Julia Reichwald
Dorothee Abramowski
Marcus Fändrich
Sathish Kumar
Haruyasu Yamaguchi
Jochen Walter
Matthias Staufenbiel
Dietmar Rudolf Thal
机构：
[1] Center of Biomedical Research,Institute of Pathology – Laboratory of Neuropathology
[2] University of Ulm,Novartis Pharma
[3] Novartis Institutes for Biomedical Research,Institute for Pharmaceutical Biotechnology
[4] Center of Biomedical Research,Department of Neurology
[5] University of Ulm,Department of Cellular Neurology
[6] University of Bonn,undefined
[7] Gunma University School of Health Sciences,undefined
[8] Hertie Institute for Clinical Brain Research,undefined
[9] University of Tübingen and DZNE,undefined
[10] German Center for Neurodegenerative Diseases,undefined
来源：
Acta Neuropathologica Communications | / 3卷
关键词：
Amyloid; Immunization; Antibody; Protofibrils; Fibrils; Clearance;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Spacial relation of amyloid plaque associated neurodegenerative and inflammatory processes in APP23 transgenic mice analyzed by confocal microscopy
    Danner, S
    Staufenbiel, M
    Wiederhold, KH
    Herzig, M
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S241 - S241
  • [32] Morphological changes in the enteric nervous system of aging and APP23 transgenic mice
    Van Ginneken, Chris
    Schaefer, Karl-Herbert
    Van Dam, Debby
    Huygelen, Veronique
    De Deyn, Peter P.
    BRAIN RESEARCH, 2011, 1378 : 43 - 53
  • [33] Impaired hypoxic tolerance in APP23 mice: a dysregulation in neuroprotective globin levels
    Van Acker, Z. P.
    Luyckx, E.
    Van Leuven, W.
    Geuens, E.
    De Deyn, P. P.
    Van Dam, D.
    Dewilde, S.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2017, 37 : 184 - 184
  • [34] Altered circadian locomotor activity in APP23 mice: a model for BPSD disturbances
    Vloeberghs, E
    Van Dam, D
    Engelborghs, S
    Nagels, G
    Staufenbiel, M
    De Deyn, PP
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2004, 20 (10) : 2757 - 2766
  • [35] Impaired hypoxic tolerance in APP23 mice: a dysregulation of neuroprotective globin levels
    Van Acker, Zoe P.
    Luyckx, Evi
    Van Leuven, Wendy
    Geuens, Eva
    De Deyn, Peter P.
    Van Dam, Debby
    Dewilde, Sylvia
    FEBS LETTERS, 2017, 591 (10) : 1321 - 1332
  • [36] Rapid Aβ turnover and reduction of amyloid plaque formation after acute and long-term inhibition of Aβ generation in APP23 mice
    Abramowski, D
    Holloway, R
    Wiederhold, KH
    Rueeger, H
    Mistl, C
    Jaton, A
    Furrer, U
    Neuenschwander, A
    Vigouret, JM
    Staufenbiel, M
    NEUROBIOLOGY OF AGING, 2004, 25 : S242 - S242
  • [37] Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and App NL-F Mice
    Parvin, Farjana
    Haglund, Samuel
    Wegenast-Braun, Bettina
    Jucker, Mathias
    Saito, Takashi
    Saido, Takaomi C.
    Nilsson, K. Peter R.
    Nilsson, Per
    Nystrom, Sofie
    Hammarstrom, Per
    ACS CHEMICAL NEUROSCIENCE, 2024, 15 (10): : 2058 - 2069
  • [38] Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA
    Senechal, Yann
    Prut, Laetitia
    Kelly, Peter H.
    Staufenbiel, Matthias
    Natt, Francois
    Hoyer, Daniel
    Wiessner, Christoph
    Dev, Kumlesh K.
    BRAIN RESEARCH, 2008, 1243 : 124 - 133
  • [39] Altered circadian locomotor activity in APP23 mice: A model for BPSD disturbances
    Vloeberghs, E
    Van Dam, D
    Engelborghs, S
    Nagels, G
    Staufenbiel, M
    De Deyn, PP
    BEHAVIOURAL PHARMACOLOGY, 2004, 15 (5-6): : A28 - A28
  • [40] The Evolution of Aβ Peptide Burden in the APP23 Transgenic Mice: Implications for Aβ Deposition in Alzheimer Disease
    Yu-Min Kuo
    Thomas G. Beach
    Lucia I. Sue
    Sarah Scott
    Kathryn J. Layne
    Tyler A. Kokjohn
    Walter M. Kalback
    Dean C. Luehrs
    Tatiana A. Vishnivetskaya
    Dorothee Abramowski
    Christine Sturchler-Pierrat
    Matthias Staufenbiel
    Roy O. Weller
    Alex E. Roher
    Molecular Medicine, 2001, 7 : 609 - 618
12345