Impact of amyloid β aggregate maturation on antibody treatment in APP23 mice

被引：0
|
作者：
Karthikeyan Balakrishnan
Ajeet Rijal Upadhaya
Julia Steinmetz
Julia Reichwald
Dorothee Abramowski
Marcus Fändrich
Sathish Kumar
Haruyasu Yamaguchi
Jochen Walter
Matthias Staufenbiel
Dietmar Rudolf Thal
机构：
[1] Center of Biomedical Research,Institute of Pathology – Laboratory of Neuropathology
[2] University of Ulm,Novartis Pharma
[3] Novartis Institutes for Biomedical Research,Institute for Pharmaceutical Biotechnology
[4] Center of Biomedical Research,Department of Neurology
[5] University of Ulm,Department of Cellular Neurology
[6] University of Bonn,undefined
[7] Gunma University School of Health Sciences,undefined
[8] Hertie Institute for Clinical Brain Research,undefined
[9] University of Tübingen and DZNE,undefined
[10] German Center for Neurodegenerative Diseases,undefined
来源：
Acta Neuropathologica Communications | / 3卷
关键词：
Amyloid; Immunization; Antibody; Protofibrils; Fibrils; Clearance;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Aggressive male APP23 mice modeling behavioral alterations in dementia
    Vloeberghs, Ellen
    Van Dam, Debby
    Coen, Katrien
    Staufenbiel, Matthias
    De Deyn, Peter Paul
    BEHAVIORAL NEUROSCIENCE, 2006, 120 (06) : 1380 - 1383
  • [22] Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice
    Sofía Fernández de Retana
    Paula Marazuela
    Montse Solé
    Guillem Colell
    Anna Bonaterra
    Jose Luis Sánchez-Quesada
    Joan Montaner
    Daniel Maspoch
    Mary Cano-Sarabia
    Mar Hernández-Guillamon
    Alzheimer's Research & Therapy, 11
  • [23] Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice
    Fitz, Nicholas F.
    Cronican, Andrea
    Pham, Tam
    Fogg, Allison
    Fauq, Abdul H.
    Chapman, Robert
    Lefterov, Iliya
    Koldamova, Radosveta
    JOURNAL OF NEUROSCIENCE, 2010, 30 (20): : 6862 - 6872
  • [24] Neurobehavioral characterization of APP23 transgenic mice with the SHIRPA primary screen
    Lalonde, R
    Dumont, M
    Staufenbiel, M
    Strazielle, C
    BEHAVIOURAL BRAIN RESEARCH, 2005, 157 (01) : 91 - 98
  • [25] Oral Administration of Synthetic Retinoid Am80 (Tamibarotene) Decreases Brain β-Amyloid Peptides in APP23 Mice
    Kawahara, Kohichi
    Nishi, Kentaro
    Suenobu, Michita
    Ohtsuka, Hideyuki
    Maeda, Akira
    Nagatomo, Kenichiro
    Kuniyasu, Akihiko
    Staufenbiel, Matthias
    Nakagomi, Madoka
    Shudo, Koichi
    Nakayama, Hitoshi
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2009, 32 (07) : 1307 - 1309
  • [26] Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice
    Fernandez de Retana, Sofia
    Marazuela, Paula
    Sole, Montse
    Colell, Guillem
    Bonaterra, Anna
    Luis Sanchez-Quesada, Jose
    Montaner, Joan
    Maspoch, Daniel
    Cano-Sarabia, Mary
    Hernandez-Guillamon, Mar
    ALZHEIMERS RESEARCH & THERAPY, 2019, 11 (1)
  • [27] Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice
    Bayer, TA
    Schäfer, S
    Simons, A
    Kemmling, A
    Kamer, T
    Tepest, R
    Eckert, A
    Schüssel, K
    Eikenberg, O
    Sturchler-Pierrat, C
    Abramowski, D
    Staufenbiel, M
    Multhaup, G
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (24) : 14187 - 14192
  • [28] Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
    Koldamova, R
    Staufenbiel, M
    Lefterov, I
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (52) : 43224 - 43235
  • [29] Age-dependent cognitive decline in the APP23 model precedes amyloid deposition
    Van Dam, D
    D'Hooge, R
    Staufenbiel, M
    Van Ginneken, C
    Van Meir, F
    De Deyn, PP
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2003, 17 (02) : 388 - 396
  • [30] Injection of exogenous amyloid-13 oligomers aggravated cognitive deficits, and activated necroptosis, in APP23 transgenic mice
    Yu, Haibo
    Morihara, Ryuta
    Ota-Elliott, Ricardo
    Bian, Zhihong
    Bian, Yuting
    Hu, Xinran
    Sun, Hongming
    Fukui, Yusuke
    Abe, Koji
    Ishiura, Hiroyuki
    Yamashita, Toru
    BRAIN RESEARCH, 2023, 1821
12345