AIEgen based light-up probes for live cell imaging

被引：0

作者：

Jing Liang

Guangxue Feng

Ryan Tsz Kin Kwok

Dan Ding

Benzhong Tang

Bin Liu

机构：

[1] National University of Singapore,Department of Chemical and Biomolecular Engineering

[2] National University of Singapore,NUS Environmental Research Institute

[3] Division of Biomedical Engineering,Department of Chemistry

[4] the Hong Kong University of Science and Technology,SCUT

[5] Guangdong Innovative Research Team,HKUST Joint Research Laboratory

[6] State Key Laboratory of Luminescent Materials and Devices,Institute of Materials Research Engineering

[7] South China University of Technology,undefined

[8] Agency for Science,undefined

[9] Technology and Research,undefined

来源：

Science China Chemistry | 2016年 / 59卷

关键词：

aggregation-induced emission (AIE); light-up probe; live cell imaging; nucleus imaging; targeted cell imaging; AIE probes;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Fluorescent light-up probes comprising a tetraphenylethene unit with aggregation-induced emission (AIE) characteristics and a water-soluble peptide have been designed and synthesized which provide cell membrane and nuclear permeability to live cells. This strategy has offered new opportunities for the development of probes with light-up ability and good signal-to-noise ratio. The selectivity or targeting specificity is determined by the peptide sequence, i.e. a nuclear localization signal that leads to nucleus imaging and a cell biomarker targeting peptide that offers specific light-up imaging of HT-29 cells.

引用

页码：53 / 61

页数：8

共 50 条

[31] Fluorescent Probes for Live Cell Imaging
Chen, Zhijie
Lukinavicius, Grazvydas
CHEMOSENSORS, 2018, 6 (03)
[32] Light-up probe
Svanvik, Nicke, 2000, Chalmers Tekniska Hogskola, Goteborg, Sweden
[33] LUCS (Light-Up Cell System), a universal high throughput assay for homeostasis evaluation in live cells
Sylvain Derick
Camille Gironde
Pierre Perio
Karine Reybier
Françoise Nepveu
Alain Jauneau
Christophe Furger
Scientific Reports, 7
[34] LUCS (Light-Up Cell System), a universal high throughput assay for homeostasis evaluation in live cells
Derick, Sylvain
Gironde, Camille
Perio, Pierre
Reybier, Karine
Nepveu, Francoise
Jauneau, Alain
Furger, Christophe
SCIENTIFIC REPORTS, 2017, 7
[35] Use of LUCS (Light-Up Cell System) as an alternative live cell method to predict human acute oral toxicity
Gironde, C.
Dufour, C.
Furger, C.
TOXICOLOGY REPORTS, 2020, 7 : 403 - 412
[36] Highly selective light-up Al3+ sensing by a coumarin based Schiff base probe: Subsequent phosphate sensing DNA binding and live cell imaging
Sheet, Sanjoy Kumar
Sen, Bhaskar
Thounaojam, Romita
Aguan, Kripamoy
Khatua, Snehadrinarayan
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2017, 332 : 101 - 111
[37] Nanomaterial-based fluorescent probes for live-cell imaging
Li, Qing
Liu, Lin
Liu, Jin-Wen
Jiang, Jian-Hui
Yu, Ru-Qin
Chu, Xia
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2014, 58 : 130 - 144
[38] Fluorescent vinblastine probes for live cell imaging
Meimetis, Labros G.
Giedt, Randy J.
Mikula, Hannes
Carlson, Jonathan C.
Kohler, Rainer H.
Pirovich, David B.
Weissleder, Ralph
CHEMICAL COMMUNICATIONS, 2016, 52 (64) : 9953 - 9956
[39] A light-up fluorescence assay for tumor cell detection based on bifunctional split aptamers
Sun, Yuqiong
Yuan, Baoyin
Deng, Meitao
Wang, Qing
Huang, Jin
Guo, Qiuping
Liu, Jianbo
Yang, Xiaohai
Wang, Kemin
ANALYST, 2018, 143 (15) : 3579 - 3585
[40] Conjugated poly(pyridinium salt)s as fluorescence light-up probes for heparin sensing
Lu, Y. (luyan@tjut.edu.cn), 1600, John Wiley and Sons Inc (131):

← 1 2 3 4 5 →