Paternal Age and Epilepsy in the Offspring

被引：0

作者：

Mogens Vestergaard

Alissa Mork

Kreesten M. Madsen

Jørn Olsen

机构：

[1] University of Aarhus,The Danish Epidemiology Science Centre, Institute of Public Health, Department of Epidemiology

[2] University of Minnesota School of Public Health,Division of Environmental and Occupational Health

[3] UCLA School of Public Health,Department of Epidemiology

[4] University of Aarhus,Institute of Public Health, Department of Epidemiology

来源：

European Journal of Epidemiology | 2005年 / 20卷

关键词：

de novo mutations; epidemiology; epilepsy; paternal age;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Advanced paternal age is associated with a higher rate of de novo mutation in sperm cells and mental disorders in the offspring. In a population based cohort study of 96,654 children, we found that fathers aged 35 years or more were slightly more likely to have a child diagnosed with epilepsy compared to fathers aged 25–29 years. Our data suggest a modest paternal effect on the aetiology of epilepsy.

引用

页码：1003 / 1005

页数：2

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