Paternal Age and Epilepsy in the Offspring

被引:0
|
作者
Mogens Vestergaard
Alissa Mork
Kreesten M. Madsen
Jørn Olsen
机构
[1] University of Aarhus,The Danish Epidemiology Science Centre, Institute of Public Health, Department of Epidemiology
[2] University of Minnesota School of Public Health,Division of Environmental and Occupational Health
[3] UCLA School of Public Health,Department of Epidemiology
[4] University of Aarhus,Institute of Public Health, Department of Epidemiology
来源
关键词
de novo mutations; epidemiology; epilepsy; paternal age;
D O I
暂无
中图分类号
学科分类号
摘要
Advanced paternal age is associated with a higher rate of de novo mutation in sperm cells and mental disorders in the offspring. In a population based cohort study of 96,654 children, we found that fathers aged 35 years or more were slightly more likely to have a child diagnosed with epilepsy compared to fathers aged 25–29 years. Our data suggest a modest paternal effect on the aetiology of epilepsy.
引用
收藏
页码:1003 / 1005
页数:2
相关论文
共 50 条
  • [21] Advanced paternal age increases risk of bipolar disorder in offspring
    Dalman, Christina
    EVIDENCE-BASED MENTAL HEALTH, 2009, 12 (02) : 59 - 59
  • [22] Advanced paternal age increased metabolic risks in mice offspring
    Mao, Yiting
    Zhao, Yiran
    Luo, Sisi
    Chen, Huixi
    Liu, Xia
    Wu, Ting
    Ding, Guolian
    Liu, Xinmei
    Sheng, Jianzhong
    Meng, Yicong
    Huang, Hefeng
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2022, 1868 (05):
  • [23] Paternal Age and Congenital Malformations in Offspring in California, 1989–2002
    Jagteshwar Grewal
    Suzan L. Carmichael
    Wei Yang
    Gary M. Shaw
    Maternal and Child Health Journal, 2012, 16 : 385 - 392
  • [24] META-ANALYSIS OF PATERNAL AGE AND SCHIZOPHRENIA RISK IN THE OFFSPRING
    Messias, Erick
    Miller, B.
    Miettunen, J.
    Lohonen, J.
    Alaraisanen, A.
    Jarvelin, M.
    Koponen, H.
    Rasanen, P.
    Kirkpatrick, B.
    Isohanni, M.
    SCHIZOPHRENIA BULLETIN, 2009, 35 : 81 - 82
  • [25] Effects of advanced paternal age on trajectories of social behavior in offspring
    Janecka, M.
    Manduca, A.
    Servadio, M.
    Trezza, V.
    Smith, R.
    Mill, J.
    Schalkwyk, L. C.
    Reichenberg, A.
    Fernandes, C.
    GENES BRAIN AND BEHAVIOR, 2015, 14 (06) : 443 - 453
  • [26] Paternal and maternal age at pregnancy and autism spectrum disorders in offspring
    Budi, Luh Putu Rihayani
    Sitaresmi, Mei Neni
    Windiani, I. Gusti Ayu Trisna
    PAEDIATRICA INDONESIANA, 2015, 55 (06) : 345 - 351
  • [27] Advanced Paternal Age and Risk of Musculoskeletal Congenital Anomalies in Offspring
    Urhoj, Stine Kjaer
    Mortensen, Laust Hvas
    Andersen, Anne-Marie Nybo
    BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY, 2015, 104 (06) : 273 - 280
  • [28] Paternal age at birth is an important determinant of offspring telomere length
    De Meyer, Tim
    Rietzschel, Ernst R.
    De Buyzere, Marc L.
    De Bacquer, Dirk
    Van Criekinge, Wim
    De Backer, Guy G.
    Gillebert, Thierry C.
    Van Oostveldt, Patrick
    Bekaert, Sofie
    HUMAN MOLECULAR GENETICS, 2007, 16 (24) : 3097 - 3102
  • [29] Paternal Age and Autism Spectrum Disorder (ASD) versus ADHD in the Offspring
    Gabis, L.
    Raz, R.
    Kesner, Y.
    Reichman, B.
    ANNALS OF NEUROLOGY, 2009, 66 : S111 - S111
  • [30] DECREASE OF LEARNING-CAPACITY IN OFFSPRING WITH INCREASING PATERNAL AGE IN THE RAT
    AUROUX, M
    TERATOLOGY, 1983, 27 (02) : 141 - 148