Mechanisms of Disease: apoptosis in heart failure—seeing hope in death

被引：0
|
作者：
Jagat Narula
Nezam Haider
Eloisa Arbustini
Y Chandrashekhar
机构：
[1] the Professor of Medicine,
[2] Chief of the Division of Cardiology,undefined
[3] Associate Dean for Research at the University of California,undefined
[4] research scientist and directs the molecular cardiology laboratory at the University of California School of Medicine,undefined
[5] Professor of Pathology at the Policlinico San Matteo,undefined
[6] University of Minnesota School of Medicine,undefined
[7] VA Medical Center,undefined
来源：
Nature Clinical Practice Cardiovascular Medicine | 2006年 / 3卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The loss of cardiomyocytes in failing or cardiomyopathic hearts is gradual and not accompanied by inflammation or major histomorphologic deformity. Apoptosis, therefore, seems to be the most logical mechanism of cell death. In this Review, Narula et al. discuss the role of apoptosis in systolic dysfunction and heart failure, and in the development of novel strategies for the management of heart failure.
引用
收藏
页码：681 / 688
页数：7
相关论文
共 50 条
  • [21] Disease Models & Mechanisms helps move heart failure to heart success
    Hooper, Kirsty
    Hmeljak, Julija
    DISEASE MODELS & MECHANISMS, 2022, 15 (05)
  • [22] Apoptosis and heart failure
    Williams, RS
    NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (10): : 759 - 760
  • [23] Apoptosis in heart failure
    Sabbah, HN
    Sharov, VG
    PROGRESS IN CARDIOVASCULAR DISEASES, 1998, 40 (06) : 549 - 562
  • [24] Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure
    Geng, YJ
    APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS, 2003, 1010 : 687 - 697
  • [25] Hope in patients hospitalized with heart failure
    Rustoen, T
    Howie, J
    Eidsmo, I
    Moum, T
    AMERICAN JOURNAL OF CRITICAL CARE, 2005, 14 (05) : 417 - 425
  • [26] Ivabradine in Heart Failure Hope or Hype?
    Deedwania, Prakash C.
    AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS, 2012, 12 (06) : 357 - 359
  • [27] FUNDAMENTAL MECHANISMS OF REGULATED CELL DEATH AND IMPLICATIONS FOR HEART DISEASE
    Del Re, Dominic P.
    Amgalan, Dulguun
    Linkermann, Andreas
    Liu, Qinghang
    Kitsis, Richard N.
    PHYSIOLOGICAL REVIEWS, 2019, 99 (04) : 1763 - 1817
  • [28] Atrial fibrillation, ischaemic heart disease, and the risk of death in patients with heart failure
    Pedersen, Ole Dyg
    Sondergaard, Peter
    Nielsen, Tonny
    Nielsen, Soren Junge
    Nielsen, Eric Steen
    Falstie-Jensen, Niels
    Nielsen, Ingolf
    Kober, Lars
    Burchardt, Hans
    Seibaek, Marie
    Torp-Pedersen, Christian
    EUROPEAN HEART JOURNAL, 2006, 27 (23) : 2866 - 2870
  • [29] Apoptosis in heart failure and the senescent heart
    Oliver Y. Bernecker
    Fawzia Huq
    E. Kevin Heist
    Bruno K. Podesser
    Roger J. Hajjar
    Cardiovascular Toxicology, 2003, 3 (3) : 183 - 190
  • [30] Congestive heart failure in chronic kidney disease: Disease-specific mechanisms of systolic and diastolic heart failure and management
    Curtis, BM
    Parfrey, PS
    CARDIOLOGY CLINICS, 2005, 23 (03) : 275 - +
12345