Dopamine neurons modulate neural encoding and expression of depression-related behaviour

被引：0

作者：

Kay M. Tye

Julie J. Mirzabekov

Melissa R. Warden

Emily A. Ferenczi

Hsing-Chen Tsai

Joel Finkelstein

Sung-Yon Kim

Avishek Adhikari

Kimberly R. Thompson

Aaron S. Andalman

Lisa A. Gunaydin

Ilana B. Witten

Karl Deisseroth

机构：

[1] Picower Institute for Learning and Memory,Department of Bioengineering

[2] Brain and Cognitive Sciences,Department of Psychiatry and Behavioral Sciences

[3] Massachusetts Institute of Technology,undefined

[4] Stanford University,undefined

[5] Neurosciences Program,undefined

[6] Stanford University,undefined

[7] Stanford University,undefined

[8] Stanford,undefined

[9] California 94305,undefined

[10] USA,undefined

[11] Howard Hughes Medical Institute,undefined

[12] Stanford University,undefined

[13] CNC Program,undefined

[14] Stanford University,undefined

来源：

Nature | 2013年 / 493卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Specific manipulation of midbrain dopamine neurons in freely moving rodents shows that their inhibition or excitation immediately modulates depression-like phenotypes that are induced by chronic mild stress, and that their activation alters the neural encoding of depression-related behaviours in the nucleus accumbens.

引用

页码：537 / 541

页数：4

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