Dopamine neurons modulate neural encoding and expression of depression-related behaviour

被引：0
|
作者：
Kay M. Tye
Julie J. Mirzabekov
Melissa R. Warden
Emily A. Ferenczi
Hsing-Chen Tsai
Joel Finkelstein
Sung-Yon Kim
Avishek Adhikari
Kimberly R. Thompson
Aaron S. Andalman
Lisa A. Gunaydin
Ilana B. Witten
Karl Deisseroth
机构：
[1] Picower Institute for Learning and Memory,Department of Bioengineering
[2] Brain and Cognitive Sciences,Department of Psychiatry and Behavioral Sciences
[3] Massachusetts Institute of Technology,undefined
[4] Stanford University,undefined
[5] Neurosciences Program,undefined
[6] Stanford University,undefined
[7] Stanford University,undefined
[8] Stanford,undefined
[9] California 94305,undefined
[10] USA,undefined
[11] Howard Hughes Medical Institute,undefined
[12] Stanford University,undefined
[13] CNC Program,undefined
[14] Stanford University,undefined
来源：
Nature | 2013年 / 493卷
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D O I：
暂无
中图分类号：
学科分类号：
摘要：
Specific manipulation of midbrain dopamine neurons in freely moving rodents shows that their inhibition or excitation immediately modulates depression-like phenotypes that are induced by chronic mild stress, and that their activation alters the neural encoding of depression-related behaviours in the nucleus accumbens.
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页码：537 / 541
页数：4
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