Comparison of Cinnarizine/Dimenhydrinate Fixed Combination with the Respective Monotherapies for Vertigo of Various OriginsA Randomized, Double-Blind, Active-Controlled, Multicentre Study

被引：0
|
作者：
Ales Hahn
Miroslav Novotný
Penko M. Shotekov
Zdenek Cirek
Irene Bognar-Steinberg
Wolfgang Baumann
机构：
[1] Charles University Prague,ENT Department
[2] Third Medical Faculty and Faculty Hospital Královské Vinohrady,ENT Clinic
[3] Masaryk University,First Neurological Clinic
[4] Medical Academy,ENT Clinic
[5] Charles University,Department of Clinical Research
[6] Hennig Arzneimittel,undefined
来源：
Clinical Drug Investigation | 2011年 / 31卷
关键词：
Fixed Combination; Benign Paroxysmal Positional Vertigo; Cinnarizine; Dimenhydrinate; Vestibular Disorder;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background and Objective: Vertigo may arise from dysfunction in the peripheral and/or the central vestibular system. Simultaneous activity of a medication at both sites will serve to improve the efficacy of antivertigo treatment. The aim of this study was to compare the efficacy and tolerability of a fixed combination of the peripherally acting cinnarizine (20 mg) plus the centrally acting dimenhydrinate (40 mg) with those of equally dosed monotherapies in the treatment of vertigo of various origins.
引用
收藏
页码：371 / 383
页数：12
相关论文
共 50 条
  • [31] Homeopathic vs conventional treatment of vertigo -: A randomized double-blind controlled clinical study
    Weiser, M
    Strösser, W
    Klein, P
    ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 1998, 124 (08) : 879 - 885
  • [32] Cariprazine in Acute Exacerbation of Schizophrenia: A Fixed-Dose, Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Trial
    Durgam, Suresh
    Cutler, Andrew J.
    Lu, Kaifeng
    Migliore, Raffaele
    Ruth, Adam
    Laszlovszky, Istvan
    Nemeth, Gyoergy
    Meltzer, Herbert Y.
    JOURNAL OF CLINICAL PSYCHIATRY, 2015, 76 (12) : E1574 - +
  • [33] Oral versus combination mesalazine therapy in active ulcerative colitis: a double-blind, double-dummy, randomized multicentre study
    Vecchi, M
    Meucci, G
    Gionchetti, P
    Beltrami, M
    Di Maurizio, P
    Beretta, L
    Ganio, E
    Usai, P
    Campieri, M
    Fornaciari, G
    De Franchis, R
    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2001, 15 (02) : 251 - 256
  • [34] Entacapone to tolcapone switch study: Multicenter double-blind, randomized, active-controlled trial in advanced Parkinson's disease
    Agid, Y
    Oertel, W
    Factor, S
    MOVEMENT DISORDERS, 2005, 20 : S94 - S94
  • [35] Safety of bazedoxifene in a randomized, double-blind, placebo- and active-controlled phase 3 study of postmenopausal women with osteoporosis
    Christiansen, Claus
    Chesnut, Charles H., III
    Adachi, Jonathan D.
    Brown, Jacques P.
    Fernandes, Cesar E.
    Kung, Annie W. C.
    Palacios, Santiago
    Levine, Amy B.
    Chines, Arkadi A.
    Constantine, Ginger D.
    BMC MUSCULOSKELETAL DISORDERS, 2010, 11
  • [36] Safety of bazedoxifene in a randomized, double-blind, placebo- and active-controlled phase 3 study of postmenopausal women with osteoporosis
    Claus Christiansen
    Charles H Chesnut
    Jonathan D Adachi
    Jacques P Brown
    César E Fernandes
    Annie WC Kung
    Santiago Palacios
    Amy B Levine
    Arkadi A Chines
    Ginger D Constantine
    BMC Musculoskeletal Disorders, 11
  • [37] Combination therapy of vitamin C and thiamine for septic shock in a multicentre, double-blind, randomized, controlled study (ATESS): study protocol for a randomized controlled trial
    Sung Yeon Hwang
    Jong Eun Park
    Ik Joon Jo
    Seonwoo Kim
    Sung Phil Chung
    Taeyoung Kong
    Jonghwan Shin
    Hui Jai Lee
    Kyoung Min You
    You Hwan Jo
    Doyun Kim
    Gil Joon Suh
    Taegyun Kim
    Won Young Kim
    Youn-Jung Kim
    Seung Mok Ryoo
    Sung-Hyuk Choi
    Tae Gun Shin
    Trials, 20
  • [38] Combination therapy of vitamin C and thiamine for septic shock in a multicentre, double-blind, randomized, controlled study (ATESS): study protocol for a randomized controlled trial
    Hwang, Sung Yeon
    Park, Jong Eun
    Jo, Ik Joon
    Kim, Seonwoo
    Chung, Sung Phil
    Kong, Taeyoung
    Shin, Jonghwan
    Lee, Hui Jai
    You, Kyoung Min
    Jo, You Hwan
    Kim, Doyun
    Suh, Gil Joon
    Kim, Taegyun
    Kim, Won Young
    Kim, Youn-Jung
    Ryoo, Seung Mok
    Choi, Sung-Hyuk
    Shin, Tae Gun
    TRIALS, 2019, 20 (1)
  • [39] IncobotulinumtoxinA for Glabellar Frown Lines in Chinese Subjects: A Randomized, Double-blind, Active-Controlled Phase-3 Study
    Wu, Yan
    Roll, Susanna
    Klein, Gudrun
    Geister, Thorin L.
    Makara, Michael A.
    Li, Bi
    PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, 2023, 11 (05) : e4956
  • [40] A Randomized, Double-Blind, Placebo- And Active-Controlled, Parallel, Nested Crossover, QT Study of Oteseconazole in Healthy Women
    Degenhardt, T.
    Darpo, B.
    Xue, H.
    Weclaw, C.
    Brand, S.
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2024, 231 (06)
12345