Comparison of Cinnarizine/Dimenhydrinate Fixed Combination with the Respective Monotherapies for Vertigo of Various OriginsA Randomized, Double-Blind, Active-Controlled, Multicentre Study

被引：0
|
作者：
Ales Hahn
Miroslav Novotný
Penko M. Shotekov
Zdenek Cirek
Irene Bognar-Steinberg
Wolfgang Baumann
机构：
[1] Charles University Prague,ENT Department
[2] Third Medical Faculty and Faculty Hospital Královské Vinohrady,ENT Clinic
[3] Masaryk University,First Neurological Clinic
[4] Medical Academy,ENT Clinic
[5] Charles University,Department of Clinical Research
[6] Hennig Arzneimittel,undefined
来源：
Clinical Drug Investigation | 2011年 / 31卷
关键词：
Fixed Combination; Benign Paroxysmal Positional Vertigo; Cinnarizine; Dimenhydrinate; Vestibular Disorder;
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摘要：
Background and Objective: Vertigo may arise from dysfunction in the peripheral and/or the central vestibular system. Simultaneous activity of a medication at both sites will serve to improve the efficacy of antivertigo treatment. The aim of this study was to compare the efficacy and tolerability of a fixed combination of the peripherally acting cinnarizine (20 mg) plus the centrally acting dimenhydrinate (40 mg) with those of equally dosed monotherapies in the treatment of vertigo of various origins.
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页码：371 / 383
页数：12
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