Factors Affecting the Clinical Development of Cytochrome P450 3A Substrates

被引：0
|
作者：
Megan A. Gibbs
Natilie A. Hosea
机构：
[1] Pfizer Inc.,Clinical Pharmacokinetics and Pharmacodynamics
[2] Pfizer Inc.,Pharmacokinetics, Dynamics and Metabolism
来源：
Clinical Pharmacokinetics | 2003年 / 42卷
关键词：
Midazolam; Ketoconazole; Felodipine; Terfenadine; Grapefruit Juice;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The objective of this review is to evaluate the risks associated with the discovery and development of cytochrome P450 (CYP) 3A substrates.
引用
收藏
页码：969 / 984
页数：15
相关论文
共 50 条
  • [31] Liver Cytochrome P450 3A Endoplasmic Reticulum-associated Degradation A MAJOR ROLE FOR THE p97 AAA ATPase IN CYTOCHROME P450 3A EXTRACTION INTO THE CYTOSOL
    Acharya, Poulomi
    Liao, Mingxiang
    Engel, Juan C.
    Correia, Maria Almira
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (05) : 3815 - 3828
  • [32] Risperidone-carbamazepine interactions: Is cytochrome P450 3A involved?
    Lane, HY
    Chang, WH
    JOURNAL OF CLINICAL PSYCHIATRY, 1998, 59 (08) : 430 - 431
  • [33] Inhibition of cytochrome P450 3A:: Relevant drug interactions in gastroenterology
    Sagir, A
    Schmitt, M
    Dilger, K
    Häussinger, D
    DIGESTION, 2003, 68 (01) : 41 - 48
  • [34] Analysis of medaka cytochrome P450 3A homotropic and heterotropic cooperativity
    Kullman, SW
    Kashiwada, S
    Hinton, DE
    MARINE ENVIRONMENTAL RESEARCH, 2004, 58 (2-5) : 469 - 473
  • [35] In silico and in vitro inhibition of cytochrome P450 3A by synthetic stilbenoids
    Basheer, Loai
    Schultz, Keren
    Guttman, Yelena
    Kerem, Zohar
    FOOD CHEMISTRY, 2017, 237 : 895 - 903
  • [36] Induction of cytochrome P450 3A by retinoids in rat hepatocyte culture
    JurimaRomet, M
    Neigh, S
    Casley, WL
    HUMAN & EXPERIMENTAL TOXICOLOGY, 1997, 16 (04): : 198 - 203
  • [37] Cytochrome P450 3A expression and activity in the human small intestine
    Yang, JS
    Tucker, GT
    Rostami-Hodjegan, A
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 76 (04) : 391 - 391
  • [38] Suppression of cytochrome P450 3A protein levels by proteasome inhibitors
    Zangar, RC
    Kocarek, TA
    Shen, S
    Bollinger, N
    Dahn, MS
    Lee, DW
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 305 (03): : 872 - 879
  • [39] Effect of Intestinal Cytochrome P450 3A on Phytochemical Presystemic Metabolism
    夏芳
    陈孝银
    Chinese Journal of Integrated Traditional and Western Medicine , 2005, (03) : 232 - 236
  • [40] Screening for cytochrome P450 3A in man: Studies with midazolam and nifedipine
    Yeates, RA
    Scharpf, F
    Laufen, H
    Zimmermann, T
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 1996, 48 (09) : 933 - 934
12345