Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo

被引:0
|
作者
Yoshihiko Uehara
Masahiro Inoue
Koji Fukuda
Hiroyuki Yamakoshi
Yoshio Hosoi
Hiroaki Kanda
Masanobu Oshima
Yoshiharu Iwabuchi
Hiroyuki Shibata
机构
[1] Tohoku University,Department of Cell Biology, Graduate School of Medicine
[2] Akita University,Department of Clinical Oncology, Graduate School of Medicine
[3] Tohoku University,Department of Organic Chemistry, Graduate School of Pharmaceutical Science
[4] Japanese Foundation for Cancer Research,Division of Pathology, Cancer Institute
[5] Kanazawa University,Division of Genetics, Cancer Research Institute
来源
Gastric Cancer | 2015年 / 18卷
关键词
Analog; β-Catenin; Curcumin; Gastric cancer; Signal transducer and activator of transcription 3;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:774 / 783
页数:9
相关论文
共 50 条
  • [21] Proton Pump Inhibitor Selectively Suppresses Proliferation and Restores the Chemosensitivity of Gastric Cancer Cells by Inhibition of STAT3 Signaling Pathway
    Zou, Xiaoping
    Huang, Shuling
    GASTROENTEROLOGY, 2013, 144 (05) : S802 - S803
  • [22] A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation
    Zhang, Xiaolei
    Sun, Ying
    Pireddu, Roberta
    Yang, Hua
    Urlam, Murali K.
    Lawrence, Harshani R.
    Guida, Wayne C.
    Lawrence, Nicholas J.
    Sebti, Said M.
    CANCER RESEARCH, 2013, 73 (06) : 1922 - 1933
  • [23] CD24 mediates gastric carcinogenesis and promotes gastric cancer progression via STAT3 activation
    Wang, Ying-Chao
    Wang, Ji-Lin
    Kong, Xuan
    Sun, Tian-Tian
    Chen, Hao-Yan
    Hong, Jie
    Fang, Jing-Yuan
    APOPTOSIS, 2014, 19 (04) : 643 - 656
  • [24] CD24 mediates gastric carcinogenesis and promotes gastric cancer progression via STAT3 activation
    Ying-Chao Wang
    Ji-Lin Wang
    Xuan Kong
    Tian-Tian Sun
    Hao-Yan Chen
    Jie Hong
    Jing-Yuan Fang
    Apoptosis, 2014, 19 : 643 - 656
  • [25] Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion
    Sun, Meng
    Liu, Chengfei
    Nadiminty, Nagalakshmi
    Lou, Wei
    Zhu, Yezi
    Yang, Joy
    Evans, Christopher P.
    Zhou, Qinghua
    Gao, Allen C.
    PROSTATE, 2012, 72 (01): : 82 - 89
  • [26] STAT3 paradoxically stimulates β-catenin expression but inhibits β-catenin function
    Ibrahem, Salih
    Al-Ghamdi, Saleh
    Baloch, Kanwal
    Muhammad, Belal
    Fadhil, Wakkas
    Jackson, Darryl
    Nateri, Abdolrahman S.
    Ilyas, Mohammad
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2014, 95 (06) : 392 - 400
  • [27] Zinc suppresses Th17 development via inhibition of STAT3 activation
    Kitabayashi, Chika
    Fukada, Toshiyuki
    Kanamoto, Minoru
    Ohashi, Wakana
    Hojyo, Shintaro
    Atsumi, Toru
    Ueda, Naoko
    Azuma, Ichiro
    Hirota, Hiroshi
    Murakami, Masaaki
    Hirano, Toshio
    INTERNATIONAL IMMUNOLOGY, 2010, 22 (05) : 375 - 386
  • [28] Inhibition of STAT3 signaling pathway by ursolic acid suppresses growth of hepatocellular carcinoma
    Liu, Tianshu
    Ma, Haiyan
    Shi, Wei
    Duan, Jialin
    Wang, Yina
    Zhang, Cuntai
    Li, Chenglong
    Lin, Jiayuh
    Li, Sheng
    Lv, Jiagao
    Lin, Li
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2017, 51 (02) : 555 - 562
  • [29] STAT3 inhibition suppresses the progression of late-stage phenotypes of Alport syndrome
    Yokota, Tsubasa
    Omachi, Kohei
    Kamura, Misato
    Kojima, Haruka
    Teramoto, Keisuke
    Kaseda, Shota
    Kuwazuru, Jun
    Fukuda, Ryosuke
    Suico, Mary Ann
    Shuto, Tsuyoshi
    Kai, Hirofumi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 133 (03) : S161 - S161
  • [30] MiR-337 suppresses pancreatic cancer development via STAT3/Wnt/β-catenin axis
    Shi, Jin
    Su, Qingliang
    Han, Fei
    Chen, Wenping
    Zhang, Donghua
    Xu, Baoli
    ANTI-CANCER DRUGS, 2021, 32 (07) : 681 - 692