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Evidence for Diminished Functional Expression of Intestinal Transporters in Caco-2 Cell Monolayers at High Passages
被引:0
|作者:
Hongshi Yu
Thomas J. Cook
Patrick J. Sinko
机构:
[1] Rutgers University,College of Pharmacy
[2] NaviCyte,undefined
[3] Inc.,undefined
来源:
关键词:
aqueous boundary layer;
brush border enzymes;
carrier-mediated transport;
diffusion chamber;
heterogeneity;
permeability;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
Purpose. To investigate the effects of passaging on the intrinsic membrane transport parameters of compounds absorbed by means of passive and carrier-mediated processes in the Caco-2 cell line.
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页码:757 / 762
页数:5
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