Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine

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作者
Ralf Buettner
Le Xuan Truong Nguyen
Corey Morales
Min-Hsuan Chen
Xiwei Wu
Lisa S. Chen
Dinh Hoa Hoang
Servando Hernandez Vargas
Vinod Pullarkat
Varsha Gandhi
Guido Marcucci
Steven T. Rosen
机构
[1] City of Hope Medical Center,Hematology Malignancies Research Institute, Gehr Family Center for Leukemia Research
[2] City of Hope Medical Center,Integrative Genomics Core, Beckman Research Institute
[3] The University of Texas MD Anderson Cancer Center,Department of Experimental Therapeutics
关键词
Acute myeloid leukemia; Oxidative phosphorylation; Fatty acid oxidation; Nucleoside analog; Metabolism;
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