Oral pulsed high-dose dexamethasone for myositis

被引：0

作者：

M. F. G. van der Meulen

J. E. Hoogendijk

J. H. J. Wokke

M. de Visser

机构：

[1] Department of Neurology,

[2] University Medical Centre,undefined

[3] PO Box 85500,undefined

[4] 3508 GA Utrecht,undefined

[5] The Netherlands e-mail address: M.F.G.vdMeulen@neuro.azu.nl Tel.: +31-30-2507978,undefined

[6] +31-30-2506480 Fax: +31-30-2522782,undefined

[7] Department of Neurology,undefined

[8] Academic Medical Centre,undefined

[9] University of Amsterdam,undefined

[10] The Netherlands,undefined

来源：

Journal of Neurology | 2000年 / 247卷

关键词：

Key words Polymyositis; Dermatomyositis; Therapy; Pulsed ¶dexamethasone;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

To study the short-term effect of oral pulsed high-dose dexamethasone for myositis we treated eight newly diagnosed patients with three 28-day cycles of oral dexamethasone. Primary outcome measures were muscle strength, pain, and serum creatine kinase activity. Six patients responded. Side effects were mild. At follow-up five responders were still in remission, without ¶medication. Pulsed high-dose ¶dexamethasone seems beneficial in myositis. A larger, prednisone-controlled trial is justified to analyze long-term efficacy.

引用

页码：102 / 105

页数：3

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