Oral pulsed high-dose dexamethasone for myositis

被引：0
|
作者：
M. F. G. van der Meulen
J. E. Hoogendijk
J. H. J. Wokke
M. de Visser
机构：
[1] Department of Neurology,
[2] University Medical Centre,undefined
[3] PO Box 85500,undefined
[4] 3508 GA Utrecht,undefined
[5] The Netherlands e-mail address: M.F.G.vdMeulen@neuro.azu.nl Tel.: +31-30-2507978,undefined
[6] +31-30-2506480 Fax: +31-30-2522782,undefined
[7] Department of Neurology,undefined
[8] Academic Medical Centre,undefined
[9] University of Amsterdam,undefined
[10] The Netherlands,undefined
来源：
Journal of Neurology | 2000年 / 247卷
关键词：
Key words Polymyositis; Dermatomyositis; Therapy; Pulsed ¶dexamethasone;
D O I：
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摘要：
To study the short-term effect of oral pulsed high-dose dexamethasone for myositis we treated eight newly diagnosed patients with three 28-day cycles of oral dexamethasone. Primary outcome measures were muscle strength, pain, and serum creatine kinase activity. Six patients responded. Side effects were mild. At follow-up five responders were still in remission, without ¶medication. Pulsed high-dose ¶dexamethasone seems beneficial in myositis. A larger, prednisone-controlled trial is justified to analyze long-term efficacy.
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页码：102 / 105
页数：3
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