Oral pulsed high-dose dexamethasone for myositis

被引:0
|
作者
M. F. G. van der Meulen
J. E. Hoogendijk
J. H. J. Wokke
M. de Visser
机构
[1] Department of Neurology,
[2] University Medical Centre,undefined
[3] PO Box 85500,undefined
[4] 3508 GA Utrecht,undefined
[5] The Netherlands e-mail address: M.F.G.vdMeulen@neuro.azu.nl Tel.: +31-30-2507978,undefined
[6] +31-30-2506480 Fax: +31-30-2522782,undefined
[7] Department of Neurology,undefined
[8] Academic Medical Centre,undefined
[9] University of Amsterdam,undefined
[10] The Netherlands,undefined
来源
Journal of Neurology | 2000年 / 247卷
关键词
Key words Polymyositis; Dermatomyositis; Therapy; Pulsed ¶dexamethasone;
D O I
暂无
中图分类号
学科分类号
摘要
To study the short-term effect of oral pulsed high-dose dexamethasone for myositis we treated eight newly diagnosed patients with three 28-day cycles of oral dexamethasone. Primary outcome measures were muscle strength, pain, and serum creatine kinase activity. Six patients responded. Side effects were mild. At follow-up five responders were still in remission, without ¶medication. Pulsed high-dose ¶dexamethasone seems beneficial in myositis. A larger, prednisone-controlled trial is justified to analyze long-term efficacy.
引用
收藏
页码:102 / 105
页数:3
相关论文
共 50 条
  • [1] Oval pulsed high-dose dexamethasone for myositis
    van der Meulen, MFG
    Hoogendijk, JE
    Wokke, JHJ
    de Visser, M
    JOURNAL OF NEUROLOGY, 2000, 247 (02) : 102 - 105
  • [2] Idiopathic thrombocytopenic purpura in pregnancy treated with pulsed high-dose oral dexamethasone
    Byrne, JD
    Incerpi, MH
    Goodwin, TM
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1997, 177 (02) : 468 - 469
  • [3] High-dose pulsed dexamethasone for immune thrombocytopenia
    Demiroglu, H
    Dundar, S
    NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (06): : 425 - 426
  • [4] Pharmacokinetics of high-dose oral and intravenous dexamethasone
    Tóth, GG
    Kloosterman, C
    Uges, DRA
    Jonkman, MF
    THERAPEUTIC DRUG MONITORING, 1999, 21 (05) : 532 - 535
  • [5] High-dose pulsed dexamethasone for immune thrombocytopenia - Reply
    Andersen, JC
    NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (06): : 426 - 427
  • [6] Oral pulsed high-dose dexamethasone therapy for rheumatic diseases: An alternative safe and effective scheme
    de Carvalho, Jozelio Freire
    Skare, Thelma
    NORTHERN CLINICS OF ISTANBUL, 2023, 10 (03) : 398 - 400
  • [7] Recalcitrant necrobiotic xanthogranuloma responding to pulsed high-dose oral dexamethasone plus maintenance therapy with oral prednisolone
    Chave, TA
    Chowdhury, MMU
    Holt, PJA
    BRITISH JOURNAL OF DERMATOLOGY, 2001, 144 (01) : 158 - 161
  • [8] High-dose dexamethasone or oral prednisone for immune thrombocytopenia?
    Godeau, Bertrand
    LANCET HAEMATOLOGY, 2016, 3 (10): : E453 - E454
  • [9] Pulsed high-dose dexamethasone in the treatment of refractory immune thrombocytopenia
    Busto, MJ
    Llamas, P
    Cabrera, R
    Fernandez, MN
    BRITISH JOURNAL OF HAEMATOLOGY, 1996, 93 (03) : 738 - 739
  • [10] Treatment of Idiopathic Headshaking in Horses with Pulsed High-Dose Dexamethasone
    Tomlinson, J. E.
    Neff, P.
    Boston, R. C.
    Aceto, H.
    Nolen-Walston, R. D.
    JOURNAL OF VETERINARY INTERNAL MEDICINE, 2013, 27 (06) : 1551 - 1554