The AP-1 transcription factor Batf controls TH17 differentiation

被引：0

作者：

Barbara U. Schraml

Kai Hildner

Wataru Ise

Wan-Ling Lee

Whitney A.-E. Smith

Ben Solomon

Gurmukh Sahota

Julia Sim

Ryuta Mukasa

Saso Cemerski

Robin D. Hatton

Gary D. Stormo

Casey T. Weaver

John H. Russell

Theresa L. Murphy

Kenneth M. Murphy

机构：

[1] Department of Pathology and Immunology,Department of Molecular Biology and Pharmacology

[2] ,Department of Pathology

[3] Howard Hughes Medical Institute,undefined

[4] ,undefined

[5] Department of Genetics,undefined

[6] ,undefined

[7] Washington University School of Medicine,undefined

[8] 660 South Euclid Avenue,undefined

[9] Saint Louis,undefined

[10] Missouri 63110,undefined

[11] USA,undefined

[12] University of Alabama at Birmingham,undefined

[13] University Station,undefined

[14] Birmingham,undefined

[15] Alabama 35294,undefined

[16] USA,undefined

来源：

Nature | 2009年 / 460卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

AP-1 (activator protein-1) transcription factors, also known as JUN factors, are broadly acting factors regulating many inducible genetic responses. Schraml et al. report a surprising mechanism that expands the biological repertoire of the AP-1 family. They find that the AP-1 transcription factor Batf plays a critical role in the differentiation of IL17-producing T-helper cells.

引用

页码：405 / 409

页数：4

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