The AP-1 transcription factor Batf controls TH17 differentiation

被引：0

作者：

Barbara U. Schraml

Kai Hildner

Wataru Ise

Wan-Ling Lee

Whitney A.-E. Smith

Ben Solomon

Gurmukh Sahota

Julia Sim

Ryuta Mukasa

Saso Cemerski

Robin D. Hatton

Gary D. Stormo

Casey T. Weaver

John H. Russell

Theresa L. Murphy

Kenneth M. Murphy

机构：

[1] Department of Pathology and Immunology,Department of Molecular Biology and Pharmacology

[2] ,Department of Pathology

[3] Howard Hughes Medical Institute,undefined

[4] ,undefined

[5] Department of Genetics,undefined

[6] ,undefined

[7] Washington University School of Medicine,undefined

[8] 660 South Euclid Avenue,undefined

[9] Saint Louis,undefined

[10] Missouri 63110,undefined

[11] USA,undefined

[12] University of Alabama at Birmingham,undefined

[13] University Station,undefined

[14] Birmingham,undefined

[15] Alabama 35294,undefined

[16] USA,undefined

来源：

Nature | 2009年 / 460卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

AP-1 (activator protein-1) transcription factors, also known as JUN factors, are broadly acting factors regulating many inducible genetic responses. Schraml et al. report a surprising mechanism that expands the biological repertoire of the AP-1 family. They find that the AP-1 transcription factor Batf plays a critical role in the differentiation of IL17-producing T-helper cells.

引用

页码：405 / 409

页数：4

共 50 条

[21] Examining the Role of AP-1 in T cell Development Through Overexpression of BATF Transcription Factors
Jordan, Kimberly L.
Betz, Briana C.
Logan, Michael R.
Taparowsky, Elizabeth J.
JOURNAL OF IMMUNOLOGY, 2009, 182
[22] The Transcription Factor BATF Controls CD8+ T Cell Effector Differentiation
Barnitz, R. Anthony
Kurachi, Makoto
Lemieux, Madeleine E.
Yosef, Nir
Dilorio, Michael A.
Yates, Kathleen B.
Godec, Jernej
Odorizzi, Pamela
Regev, Aviv
Wherry, E. John
Haining, W. Nicholas
BLOOD, 2013, 122 (21)
[23] Specific suppression of the transcription factor AP-1 by mepacrine
Stuhlmeier, K. M.
Linnert, C.
Broell, H.
ARTHRITIS RESEARCH & THERAPY, 2001, 3 (Suppl 2)
[24] Specific suppression of the transcription factor AP-1 by mepacrine
KM Stuhlmeier
C Linnert
H Bröll
Arthritis Research & Therapy, 3
[25] REGULATION OF HANP GENE BY THE TRANSCRIPTION FACTOR AP-1
KOVACICMILIVOJEVIC, B
GARDNER, DG
HYPERTENSION, 1994, 24 (03) : 388 - 388
[26] ICER controls Th17 cell differentiation and autoimmune pathology
Yoshida, Nobuya
Mizui, Masayuki
Otomo, Kotaro
Koga, Tomohiro
Bradley, Sean
Comte, Denis
Rosetti, Florencia
Kyttaris, Vasileios
Crispin, Jose
Tsokos, George
JOURNAL OF IMMUNOLOGY, 2015, 194
[27] Foxp3 controls Treg/Th17 differentiation
Ziegler, S. F.
IMMUNOLOGY, 2008, 125 : 56 - 57
[28] The transcription factor AP-1 regulates RANKL-dependent differentiation and survival in osteoclasts.
Ikeda, F
Matubara, T
Hata, K
Yamashita, K
Watanabe, T
Kukita, T
Yoshioka, K
Nishimura, R
Yoneda, T
JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 : S257 - S257
[29] The AP-1 factors FOSL1 and FOSL2 regulate transcriptional networks governing early human Th17 cell differentiation
Shetty, Ankitha
Tripathi, Subhash Kumar
Junttila, Sini
Buchacher, Tanja
Biradar, Rahul
Bhosale, Santosh D.
Envall, Tapio
Laiho, Asta
Moulder, Robert
Rasool, Omid
Galande, Sanjeev
Elo, Laura L.
Lahesmaa, Riitta
EUROPEAN JOURNAL OF IMMUNOLOGY, 2021, 51 : 159 - 159
[30] Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation
Ouyang, Xinshou
Zhang, Ruihua
Yang, Jianjun
Li, Qingshan
Qin, Lihui
Zhu, Chen
Liu, Jianguo
Ning, Huan
Shin, Min Sun
Gupta, Monica
Qi, Chen-Feng
He, John Cijiang
Lira, Sergio A.
Morse, Herbert C., III
Ozato, Keiko
Mayer, Lloyd
Xiong, Huabao
NATURE COMMUNICATIONS, 2011, 2

← 1 2 3 4 5 →