Exosomes from adipose tissue-derived mesenchymal stem cells ameliorate histone-induced acute lung injury by activating the PI3K/Akt pathway in endothelial cells

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作者
Yukie Mizuta
Tomohiko Akahoshi
Jie Guo
Shuo Zhang
Sayoko Narahara
Takahito Kawano
Masaharu Murata
Kentaro Tokuda
Masatoshi Eto
Makoto Hashizume
Ken Yamaura
机构
[1] Kyushu University,Department of Disaster and Emergency Medicine, Graduate School of Medical Sciences
[2] Kyushu University,Department of Anesthesiology and Critical Care Medicine, Graduate School of Medical Sciences
[3] Kyushu University Hospital,Emergency and Critical Care Center
[4] Kyushu University,Center for Advanced Medical Innovation
[5] Kyushu University Hospital,Intensive Care Unit
关键词
Sepsis; Acute lung injury; Acute respiratory distress syndrome; Histones; Endothelial damage; Adipose-derived mesenchymal stem cells; Exosomes; PI3K/Akt signaling pathway; miR-126;
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