Preparation and degradation characteristics of poly (d, l-lactide) composite films

被引：0
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作者：
Lei Chen
Yuhua Yan
Jianhua Li
Shipu Li
机构：
[1] Wuhan University of Technology,Biomedical Materials and Engineering Research Center
来源：
Journal of Wuhan University of Technology-Mater. Sci. Ed. | 2007年 / 22卷
关键词：
poly (d, l-lactic acid) (PDLLA); chitosan (CHI); -TCP; nerve growth factor (NGF); degradation characteristics;
D O I：
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学科分类号：
摘要：
PDLLA/CHI/β-TCP/NGF composite films were prepared by a solvent evaporation method. The degradation characteristics of the poly (d, l-lactide) composite films were studied in vitro and in vivo. The acidity produced by poly (d, l-lactide) materials was not obvious. Adding chitosan and β-TCP can relieve the acidity problem and improve strength performance of films. The NGF has influences on the degradation characteristics of films. It is verified that PDLLA/CHI/β-TCP/NGF composite films prepared by solvent evaporation method have excellent degradation characteristics. It can be used as a perfect biomaterial for repairing nerve injuries.
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