The Mechanism of Presynaptic Long-Term Depression Mediated by Group I Metabotropic Glutamate Receptors

被引：0
|
作者：
Yuansheng Tan
Nobuaki Hori
David O. Carpenter
机构：
[1] University at Albany,Department of Environmental Health and Toxicology, School of Public Health
来源：
Cellular and Molecular Neurobiology | 2003年 / 23卷
关键词：
hippocampus; metabotropic glutamate receptors; calcium; presynaptic; ionophoretic responses; DHPG; AMPA; NMDA; kainate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
1. Metabotropic glutamate receptors (mGluRs) are known to play a role in synaptic plasticity. In a study of rat hippocampal brain slices, we find that a brief perfusion of a group I mGluR agonist, (S)-3,5-dihydroxyphenylglycine (DHPG), induced a robust long-term depression (DHPG-LTD) in area CA1.
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页码：187 / 203
页数：16
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