The Mechanism of Presynaptic Long-Term Depression Mediated by Group I Metabotropic Glutamate Receptors

被引：0

作者：

Yuansheng Tan

Nobuaki Hori

David O. Carpenter

机构：

[1] University at Albany,Department of Environmental Health and Toxicology, School of Public Health

来源：

Cellular and Molecular Neurobiology | 2003年 / 23卷

关键词：

hippocampus; metabotropic glutamate receptors; calcium; presynaptic; ionophoretic responses; DHPG; AMPA; NMDA; kainate;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

1. Metabotropic glutamate receptors (mGluRs) are known to play a role in synaptic plasticity. In a study of rat hippocampal brain slices, we find that a brief perfusion of a group I mGluR agonist, (S)-3,5-dihydroxyphenylglycine (DHPG), induced a robust long-term depression (DHPG-LTD) in area CA1.

引用

页码：187 / 203

页数：16

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