Synthesis and Antimicrobial Studies of Some Novel Pyrazoline and Isoxazoline Derivatives

被引：0
|
作者：
Jadhav, S. B. [1 ]
Shastri, R. A. [1 ]
Gaikwad, K. V. [1 ]
Gaikwad, S. V. [1 ]
机构：
[1] Milind Coll Sci, PG Dept Chem, Aurangabad 431001, Maharashtra, India
来源：
E-JOURNAL OF CHEMISTRY | 2009年 / 6卷
关键词：
Chalcones; 2-Pyrazolines; 2-Isoxazolines; Antimicrobial activity; ANTICONVULSANT ACTIVITIES; ANTIDEPRESSANT;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of 1H-3-(4'-substituted phenyl)-5-(6''-methoxy napthaline)-2-pyrazolines (4a-e) and 1H-3-(4'-substituted phenyl)-5-(6''-methoxynapthaline)-2-isoxazolines (5a-e) were synthesized by reacting 1-(4'-substituted phenyl)-3-(6''-methoxynapthaline)-2-propene-1-one (3a-e) with hydrazine hydrate and hydroxylamine hydrochloride respectively. All these compounds were characterized by means of their IR, (1)H NMR, spectroscopic data and microanalysis. All the synthesized products were evaluated for their antimicrobial activity. All the compounds exhibited significant to moderate antimicrobial activity.
引用
收藏
页码：S183 / S188
页数：6
相关论文
共 50 条
  • [41] Synthesis and antimicrobial studies of some novel series of fused naphthopyranotetrazole derivatives
    Kanakaraju, S.
    Chandramouli, G. V. P.
    RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (05) : 2809 - 2822
  • [42] Synthesis, Antimicrobial and Cytotoxicity Studies of Some Novel Modified Strobilurin Derivatives
    Sridhara, Ajjanna M.
    Reddy, Kallam R. Venugopala
    Keshavayya, Jathi
    Ambika, Dasannana Malige S.
    Gopinath, Vadiraj S.
    Bose, Prosenjit
    Goud, Sanath Kumar
    Peethambar, Sanenahalli K.
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2011, 22 (05) : 849 - U59
  • [43] Synthesis and antimicrobial activity of some indole derivatives containing pyrazoline and benzodiazepine systems
    Saundane, AR
    Badiger, J
    Sharma, PMV
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2005, 14 (04) : 331 - 334
  • [44] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW PYRAZOLINE DERIVATIVES
    Ozdemir, A.
    Turan-Zitouni, G.
    Kaplancikli, Z. A.
    Altintop, M. D.
    Demirci, F.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 44 : 165 - 166
  • [45] Synthesis of pyrazoline and isoxazoline in triethanolamine medium
    Agrawal, NN
    Soni, PA
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2004, 43 (12): : 2700 - 2701
  • [46] SYNTHESIS OF AZASTEROIDS WITH PYRAZOLINE AND ISOXAZOLINE RINGS
    SIDDIQUI, AH
    SATYANARAYANA, Y
    SRINIVAS, M
    RAJESHWAR, K
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1992, 69 (12) : 846 - 848
  • [47] Synthesis of some hydrazone and pyrazoline derivatives
    Pakistan Journal of Scientific and Industrial Research, 38 (5-6):
  • [48] Synthesis and antimicrobial activity of novel quinoline derivatives bearing pyrazoline and pyridine analogues
    Nisheeth C. Desai
    Bonny Y. Patel
    Bharti P. Dave
    Medicinal Chemistry Research, 2017, 26 : 109 - 119
  • [49] Synthesis and characterization of novel benzimidazole bearing pyrazoline derivatives as potential antimicrobial agents
    N. C. Desai
    D. D. Pandya
    G. M. Kotadiya
    Priyanka Desai
    Medicinal Chemistry Research, 2014, 23 : 1474 - 1487
  • [50] Synthesis and characterization of novel benzimidazole bearing pyrazoline derivatives as potential antimicrobial agents
    Desai, N. C.
    Pandya, D. D.
    Kotadiya, G. M.
    Desai, Priyanka
    MEDICINAL CHEMISTRY RESEARCH, 2014, 23 (03) : 1474 - 1487
12345