Synthesis and Antimicrobial Studies of Some Novel Pyrazoline and Isoxazoline Derivatives

被引：0
|
作者：
Jadhav, S. B. [1 ]
Shastri, R. A. [1 ]
Gaikwad, K. V. [1 ]
Gaikwad, S. V. [1 ]
机构：
[1] Milind Coll Sci, PG Dept Chem, Aurangabad 431001, Maharashtra, India
来源：
E-JOURNAL OF CHEMISTRY | 2009年 / 6卷
关键词：
Chalcones; 2-Pyrazolines; 2-Isoxazolines; Antimicrobial activity; ANTICONVULSANT ACTIVITIES; ANTIDEPRESSANT;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of 1H-3-(4'-substituted phenyl)-5-(6''-methoxy napthaline)-2-pyrazolines (4a-e) and 1H-3-(4'-substituted phenyl)-5-(6''-methoxynapthaline)-2-isoxazolines (5a-e) were synthesized by reacting 1-(4'-substituted phenyl)-3-(6''-methoxynapthaline)-2-propene-1-one (3a-e) with hydrazine hydrate and hydroxylamine hydrochloride respectively. All these compounds were characterized by means of their IR, (1)H NMR, spectroscopic data and microanalysis. All the synthesized products were evaluated for their antimicrobial activity. All the compounds exhibited significant to moderate antimicrobial activity.
引用
收藏
页码：S183 / S188
页数：6
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