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One-pot synthesis of a novel compound N-hydroxydeca-hydroacridine under microwave irradiation
被引:19
|作者:
Tu, SJ
[1
]
Fang, F
[1
]
Zhu, SL
[1
]
Li, TJ
[1
]
Zhang, XJ
[1
]
Zhuang, QY
[1
]
机构:
[1] Xuzhou Normal Univ, Dept Chem, Key Lab Biotechnol Med Plant, Xuzhou 221009, Jiangsu, Peoples R China
关键词:
D O I:
10.1002/jhet.5570410519
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
A novel reaction to synthesis a series new N-hydroxyldecahydroacridine derivatives by a one-pot condensation of aldehyde, 1,3-dicarbonyl compound and NH2OH in glycol under microwave irradiation is described. N-hydroxyldecahydroacridine was obtained in excellent yields (81-95%) within short reaction time (4-7 min).
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页码:767 / 770
页数:4
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