An Effective, One-Pot Synthesis of Fully Substituted Pyridines under Microwave Irradiation in the Absence of Solvent

被引：4
|
作者：
Yang, Xiao-Hui [1 ,2 ,3 ]
Zhou, Yong-Hong [1 ,2 ,3 ]
Zhang, Ping-Hu [4 ,5 ]
Zhang, Li-Yun [1 ,2 ,3 ]
机构：
[1] CAF, Inst Chem Ind Forestry Prod, Nanjing 210042, Jiangsu, Peoples R China
[2] Key Lab Forest Chem Engn, Natl Engn Lab Biomass Chem Utilizat, Nanjing 210042, Jiangsu, Peoples R China
[3] Key Lab Biomass Energy & Mat, Nanjing 210042, Jiangsu, Peoples R China
[4] China Pharmaceut Univ, Jiangsu Ctr New Drug Screening, Nanjing 210009, Peoples R China
[5] China Pharmaceut Univ, Natl Drug Screening Lab, Nanjing 210009, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2013年 / 50卷 / 06期
关键词：
MULTICOMPONENT REACTIONS; 3-COMPONENT SYNTHESIS; FACILE SYNTHESIS; ONE-STEP; DERIVATIVES; SEPARATION; ALDEHYDES; VANILLIN; RECEPTOR;
D O I：
10.1002/jhet.1035
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient, rapid, and environmentally benign protocol is described for the preparation of fully substituted pyridine derivativesvia four-component reactions between 2-substituted acetophenones, aromatic aldehydes, malononitrile, and ammonium acetate under microwave irradiation with good yield and without solvent.
引用
收藏
页码：1346 / 1350
页数：5
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