Evaluation of the antioxidant and cytotoxic activities of zinc oxide nanoparticles synthesized using scutellaria baicalensis root

被引：48
|
作者：
Tettey, C. O. [1 ]
Shin, H. M. [2 ]
机构：
[1] Univ Hlth & Allied Sci, Sch Basic & Biomed Sci, Dept Biomed Sci, Ho, Ghana
[2] Dongguk Univ, Coll Korean Med, Dept Physiol, Gyeongju, South Korea
来源：
SCIENTIFIC AFRICAN | 2019年 / 6卷
关键词：
Green synthesis; Scutellaria baicalensis; ZnONPs; Antioxidants; Cytotoxicity; OXIDATIVE STRESS;
D O I：
10.1016/j.sciaf.2019.e00157
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The authors describe a simple green method for the preparation of zinc oxide nanoparticles (ZnONPs) using the aqueous root extract of Scutellaria baicalensis. The synthesized ZnONPs were characterized by UV-Vis spectroscopy, FTIR, TEM, SEM and EDX. They were spherical in shape and with sizes ranging from 33.14-99.03 nm. The ZnONPs produced exhibited significant free radical scavenging effects. An in-vitro study showed a dose-dependent cytotoxic effect on HeLa cells. (C) 2019 Published by Elsevier B.V.
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页数：7
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