Process Development of Selectively Benzoylated and Fluorinated Glycosyl Donors

被引：14

作者：

Weibeith, Franz J. ^{[1
]}

Gill, Harpal S. ^{[1
]}

Jiang, Ying ^{[1
]}

Lee, George E. ^{[1
]}

Lienard, Philippe ^{[1
]}

Pemberton, Clive ^{[1
]}

Powers, Matthew R. ^{[1
]}

Subotkowski, Witold ^{[1
]}

Tomasik, Witold ^{[1
]}

Vanasse, Benoit J. ^{[1
]}

Yu, Yong ^{[1
]}

机构：

[1] Sanofi Aventis US, Chem Dev, Bridgewater, NJ 08807 USA

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2010年 / 14卷 / 03期

关键词：

DERIVATIVES; GLUCOSE; ALPHA; TRIFLUORIDE; MECHANISM; GALACTOSE;

D O I：

10.1021/op100053k

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Route selection, process development and large-scale preparation of selectively benzoylated and fluorinated D-glucopyranoses, required as glycosyl donors for the synthesis of the SGLT inhibitor SAR7226, are discussed.

引用

页码：623 / 631

页数：9

共 50 条

[41] THE USE OF THIOGLYCOSIDES AS GLYCOSYL DONORS IN OLIGOSACCHARIDE SYNTHESIS
SILWANIS, BA
DASGUPTA, F
GAREGG, PJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1988, 195 : 92 - CARB
[42] Trichloroacetimidates as glycosyl donors in recyclable ionic liquids
Poletti, L
Rencurosi, A
Lay, L
Russo, G
SYNLETT, 2003, (15) : 2297 - 2300
[43] Exploring glycosyl sulphates as donors for chemical glycosylation
Imperio, Daniela
Campo, Federica
Panza, Luigi
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 19 (22) : 4930 - 4936
[44] Stereoselective glycosylation using oxathiane glycosyl donors
Fascione, Martin A.
Adshead, Sophie J.
Stalford, Susanne A.
Kilner, Colin A.
Leach, Andrew G.
Turnbull, W. Bruce
CHEMICAL COMMUNICATIONS, 2009, (39) : 5841 - 5843
[45] The use of anhydroiminocyclitols as glycosyl donors in glycosidation reactions
Fuentes, Jose
Al Bujuq, Nader R.
Angulo, Manuel
Gasch, Consolacion
TETRAHEDRON, 2010, 66 (47) : 9214 - 9222
[46] Synthesis of Glycoporphyrins Using Trichloroacetimidates as Glycosyl Donors
Aicher, Daniel
Wiehe, Arno
Stark, Christian B. W.
SYNLETT, 2010, (03) : 395 - 398
[47] Glycosyl Esters as Stable Donors in Chemical Glycosylation
Pareek, Sumit
Mandadi, Pavan
Rao Sanapala, Someswara
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2025,
[48] Use of acyclic glycosyl donors for furanoside synthesis
McAuliffe, JC
Hindsgaul, O
JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (05): : 1234 - 1239
[49] Novel stereoelectronic behavior of bicyclic glycosyl donors
Dios, A
Franck, RW
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 216 : U594 - U594
[50] Propargyl/methyl furanosides as potential glycosyl donors
Vidadala, Srinivasa Rao
Gayatri, Gaddamannugu
Sastry, G. Narahari
Hotha, Srinivas
CHEMICAL COMMUNICATIONS, 2011, 47 (35) : 9906 - 9908

← 1 2 3 4 5 →