Asymmetric organocopper chemistry: Cu-catalyzed conjugate addition and allyfic substitution

被引：0

作者：

Alexakis, A ^{[1
]}

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

来源：

METHODOLOGIES IN ASYMMETRIC CATALYSIS | 2004年 / 880卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review deals with the most recent developments in the asymmetric conjugate addition and allylic substitution. For the conjugate addition, the best enantioselectivities (>99%) have been attained with dialkylzinc reagents and 0.5-2% CuX and 1-4% of a chiral trivalent phosphorus ligand. The gamma-allylic substitution can be achieved equally well with, either dialkylzinc or Grignard reagents, and the same catalysts.

引用

页码：43 / 59

页数：17

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