Asymmetric organocopper chemistry: Cu-catalyzed conjugate addition and allyfic substitution

被引：0
|
作者：
Alexakis, A [1 ]
机构：
[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland
来源：
METHODOLOGIES IN ASYMMETRIC CATALYSIS | 2004年 / 880卷
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This review deals with the most recent developments in the asymmetric conjugate addition and allylic substitution. For the conjugate addition, the best enantioselectivities (>99%) have been attained with dialkylzinc reagents and 0.5-2% CuX and 1-4% of a chiral trivalent phosphorus ligand. The gamma-allylic substitution can be achieved equally well with, either dialkylzinc or Grignard reagents, and the same catalysts.
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页码：43 / 59
页数：17
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