Rhythmoinotropic Myocardial Reactions in Rats with Postinfarction Cardiosclerosis against the Background of Streptozotocin-Induced Diabetes

被引：2
|
作者：
Kondtratieva, D. S. [1 ]
Afanasiev, S. A. [1 ]
Rebrova, T. Yu. [1 ]
Tsapko, L. P. [1 ]
Karpov, R. S. [1 ]
机构：
[1] Russian Acad Med Sci, Inst Cardiol, Tomsk Res Ctr, Siberian Div, Moscow 109801, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 148卷 / 02期
关键词：
rhythmoinotropic reaction; diabetes; postinfarction cardiosclerosis; sarcoplasmic reticulum; HEART-FAILURE; RYANODINE RECEPTOR;
D O I：
10.1007/s10517-009-0675-z
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We studied rhythmoinotropic reactions of the myocardium in rats with postinfarction cardiosclerosis and in rats with postinfarction cardiosclerosis against the background of streptozotocin-induced diabetes. Inotropic myocardial response in rats with postinfarction cardiosclerosis was significantly inhibited after rest periods, while in streptozotocin diabetic rats the rhythmoinotropic myocardial reaction was comparable with the reaction of intact myocardium. The combination of postinfarction cardiosclerosis and diabetes paradoxically contributed to preservation of contractile function of the myocardium in rats.
引用
收藏
页码：181 / 183
页数：3
相关论文
共 50 条
  • [21] Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats
    Norton, GR
    Candy, G
    Woodiwiss, AJ
    CIRCULATION, 1996, 93 (10) : 1905 - 1912
  • [22] Effect of streptozotocin-induced diabetes on myocardial blood flow reserve assessed by myocardial contrast echocardiography in rats
    Bernard Cosyns
    Steven Droogmans
    Sophie Hernot
    Céline Degaillier
    Christian Garbar
    Caroline Weytjens
    Bram Roosens
    Danny Schoors
    Tony Lahoutte
    Philippe R Franken
    Guy Van Camp
    Cardiovascular Diabetology, 7
  • [23] Effect of streptozotocin-induced diabetes on myocardial blood flow reserve assessed by myocardial contrast echocardiography in rats
    Cosyns, Bernard
    Droogmans, Steven
    Hernot, Sophie
    Degaillier, Celine
    Garbar, Christian
    Weytjens, Caroline
    Roosens, Bram
    Schoors, Danny
    Lahoutte, Tony
    Franken, Philippe R.
    Van Camp, Guy
    CARDIOVASCULAR DIABETOLOGY, 2008, 7 (1)
  • [24] Oxidative modification of proteins and antioxidant status in blood of the rats with experimental acute generalized peritonitis against the background of streptozotocin-induced diabetes
    Verveha, B. M.
    Gutyj, B., V
    Lishchuk, S. H.
    Holubiev, M. I.
    Mylostyvyi, R., V
    REGULATORY MECHANISMS IN BIOSYSTEMS, 2023, 14 (02) : 260 - 265
  • [25] HEPATIC TRANSPORT OF BILIRUBIN IN RATS WITH STREPTOZOTOCIN-INDUCED DIABETES
    TUNON, MJ
    GONZALEZ, P
    GARCIAPARDO, LA
    GONZALEZ, J
    JOURNAL OF HEPATOLOGY, 1991, 13 (01) : 71 - 77
  • [26] CEREBRAL-LESIONS IN RATS WITH STREPTOZOTOCIN-INDUCED DIABETES
    MUKAI, N
    HORI, S
    POMEROY, M
    ACTA NEUROPATHOLOGICA, 1980, 51 (01) : 79 - 84
  • [27] Antioxidant therapy and streptozotocin-induced diabetes in pregnant rats
    Kinalski, M
    Sledziewski, A
    Telejko, B
    Zarzycki, W
    Kinalska, I
    ACTA DIABETOLOGICA, 1999, 36 (03) : 113 - 117
  • [28] ALTERED MICROVASCULAR REACTIVITY IN STREPTOZOTOCIN-INDUCED DIABETES IN RATS
    HILL, MA
    LARKINS, RG
    AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 257 (05): : H1438 - H1445
  • [29] PATTERNS OF NUTRIENT SELECTION IN RATS WITH STREPTOZOTOCIN-INDUCED DIABETES
    KANAREK, RB
    HO, L
    PHYSIOLOGY & BEHAVIOR, 1984, 32 (04) : 639 - 645
  • [30] EFFECTS OF GHRELIN TREATMENT ON RATS WITH STREPTOZOTOCIN-INDUCED DIABETES
    Hadzhibozheva, P.
    Georgiev, T.
    Kalfin, R.
    Ilieva, G.
    Tolekova, A.
    JOURNAL OF PEPTIDE SCIENCE, 2014, 20 : S252 - S253
12345